Immunotherapy: Open Access
Open Access

Department of Neurosurgery, The Affiliated Changzhou No.2 People’s Hospital, Nanjing Medical University, 68 Gehu Road, 213000, Changzhou, Jiangsu, China

Publications

• Research Article   
  Endothelial Cells Immune-related Genes Risk Signature Correlated with Tumor Immune Microenvironment Predicts Therapeutic Response and Prognosis in Glioblastoma
  Author(s): Fang Liu*, Qijun Xie, Yuwei Zhang, Haoran Wang and Wu Huang
  
  Glioblastoma (GBM) is the most common and aggressive primary tumor of the central nervous system with high recurrence and extremely poor prognosis. Multiple recent studies have indicated a pivotal correlation between GBM prognosis and immune-related risk signature. Nevertheless, the potential value of Endothelial Cells (EC’s) Immune-Related Genes (EIRG’s) in prognosis, immune infiltration, and their correlation with therapeutic response to immunotherapy and TMZ chemotherapy remain obscure, especially in GBM. Here, we screened out 11 EIRG’s after intersecting the identified 59 GBM EC’s related prognostic genes and the identified 438 immune-related prognostic genes. A prognostic-related 6-EIRG’s signature was established through univariate Cox analysis and Least Absolute Shrinkage and Selection Operator (LASSO) Cox regression analysis, and patien.. View More»
  DOI: 10.35248/2471-9552.22.8.196

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