Gynecology & Obstetrics
Open Access
ISSN: 2161-0932
ISSN: 2161-0932
School of Medical Laboratory Sciences, Institute of Health, Jimma University, Jimma, Ethiopia
Review Article
Congenital Cytomegalovirus Infections: (no) Focus on Africa: a Review
Author(s): Mengistu Hailemariam*, Zeleke Mekonnen, Geert Claeys and Elizaveta Padalko
Cytomegalovirus (CMV) infection during pregnancy is a major cause of congenital infection worldwide. Congenital CMV (cCMV) infection can result in significant morbidity, mortality, or long-term sequelae, including sensorineural hearing loss. Although the increase of awareness and international guidelines on the management of cCMV is observed across the developed country, data in Africa on rates of congenital and maternal CMV infection are rather scarce and scattered. Published data are compiled in this review indicating a high pooled prevalence of CMV IgG among pregnant women in Africa (87.4%, range of 72-100%) as well as pooled reported cCMV prevalence in the newborn (3.3 %.. View More»