Clinical Pediatrics: Open Access
Open Access

Department of Pediatric, Longhua Hospital Affiliated to Shanghai University of TCM, Shanghai, China

Publications

• Research Article   
  Qingfei Tongluo Formula Attenuated Pulmonary Inflammation and Embolism in Mycoplasma Pneumonia Mice
  Author(s): Yonghong Jiang*, Zhen Xiao, Zhiyan Jiang, Xiaoyang Zhao and Jiajia Lv
  
  Ethno pharmacological relevance: Qingfei Tongluo formular (QT) is a homemade agent for the Mycoplasma Pneumonia (MPP) treatment developed by pediatrics of Shanghai Longhua hospital, which combining with azithromycin has better clinical curative effect. This study aims at exploring the chemical components and clarifying the possible mechanism involved in. Materials and methods: LC-MS was used for chemical analysis. The mycoplasma pneumoniae infected mice were treated with AZM and QT (46.25 and 92.5 mg/g) for 3 days. Polymorph nuclear neutrophils (PMNs) and monocytes in Bronchoalveolar Lavage Fluid (BALF) were measured by haemacytometer. IL-6, IL-10, IL-1β and IL-13 in BALF were identified by ELISA assay. HE staining was employed for histological examination. TLR4, COX-2 and NF-κB expressions were assessed by western blot. .. View More»
  DOI: 10.35248/2572-0775.23.8.232

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