Journal of Clinical Toxicology
Open Access

7^th Euro-Global Summit on Toxicology & Applied Pharmacology

October 24-26, 2016 Rome, Italy

Scientific Tracks Abstracts

• Nanomedicines in the European translational process

  Susanne Bremer Hoffmann

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• Development of novel targeted therapies for triple negative breast cancer: Targeting EF2-kinase

  Bulent Ozpolat

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• Change of rodent carcinogenicity testing

  Gerd Bode and Jan Willem van der Laan

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• Attenuation of adverse health effects of metallic nanoparticles with innocuous bioprotectors: Mechanistic hypotheses and experimental results

  I A Minigalieva, B A Katsnelson, L I Privalova, M P Sutunkova, V B Gurvich, O H Makeyev, I E Valamina, V Y Shur and E V Shishkina

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• Blood cancers from environmental exposure near an oil refinery

  James Dahlgren and Patrick Talbott

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• Urine sediment as DNA source in the study of susceptibility biomarkers

  Pieranna Chiarella, Damiano Carbonari, Pasquale Capone, Delia Cavallo, Sergio Iavicoli, Antonella Mansi, Renata Sisto and Giovanna Tranfo

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• Oxidized graphene exhibits toxicity toward single-celled eukaryotes

  Yazan Akkam, Rob Sleezer, Ravi Barabote, Gregory Salamo, Ralph Henry and David McNabb

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• Crime, re-offense and substance abuse of patients with severe mental disorder

  Jose Fernando Santos Almeida and Diana Moreira

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• The insect repellent N,N-diethyl-m-toluamide (DEET) induces angiogenesis via allosteric modulation of the M3 muscarinic receptor in endothelial cells

  Samuel Legeay

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• Targeted screening of succinic semialdehyde dehydrogenase deficiency (SSADHD) employing an enzymatic assay for γ-hydroxybutyric acid (GHB) in biofluids

  Cedric Wernli

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• Characterization and regulation of the expression of drug transporters in human skin

  Hanan Osman Ponchet

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• Vancomycin-induced skin eruptions with susceptibility alleles to SJS/TEN

  Liping Yang

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• Kidney cell assays for in vitro safety profiling of single stranded oligonucleotides

  Marcel Gubler

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• East Indian sandalwood oil (EISO) alleviates inflammatory and proliferative pathologies of psoriasis

  Manju Sharma, Corey Levenson, Ian Clements, Paul Castella and Michael E Cox

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• Fall in leukocyte count for monitoring of immunosuppressive and anti-cancer drug therapy

  Frieder Keller

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• Evaluation of the effects of experimental PCB toxication on oxidative and antioxidative status in central nervous systems tissues and the protective effect of curcumin

  Halef Okan Dogan, Eray Alciqir, Begum Yurdakök, Kubra Dogan, Sevil Atasoy and Fatma Meric Yilmaz

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• Natural and synthetic cannabinoids: The good, the bad, and the tragic

  Anna Radominska Pandya

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• Endothelin modulation of the cyclosporine/NSAIDs cardiovascular and renal interactions

  Mahmoud M El Mas

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• Effect of exposure area on nerve agent absorption through skin in vitro

  Christopher Dalton

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• Folic acid and vitamin B12 as possible panacea against nicotine induced pancreatic β-cell apoptosis and dysfunction

  Sandip Mukherjee and Ankita Bhattacharjee

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• Guidance on the selection of cohorts for extended one-generation reproduction toxicity study (OECD 443)

  Alan Poole

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• Co-treatment with PCBs potenciates Cd nephrotoxicity

  Vesna Matovic

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• Potentialities of synchrotron radiation (SR) fourier transform infrared microscopy (FTIRM) for environmental toxicology and pharmacology

  Lisa Vaccari

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• Effects of linuron on a rooted aquatic macrophyte in sediment-dosed test systems

  Gertie H P Arts and Helena Buresova

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• Nickel related Staphylococcus aureus infections in atopic dermatitis

  Anna Magdalena Bogdali

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• Coal-burning type of endemic fluorosis in China - From basic research to clinic prevention

  Zhi-Zhong Guan

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• Assessment of levels of heavy metals in fluted pumpkin (Telfairia occidentalis) leaves planted at varying distances away from mega refueling service stations in Nigeria

  Uduak Luke, F E Uboh and Hope Cletus

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• 137Cs in soil and milk in the region of Zagreb, Croatia

  Branko Petrinec, Iva Franulovic, Marko Šoštaric, Dinko Babic, Zdenko Franic and Gordana Marovic

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• Converging effects of a PCB mixture, bisphenol A and chlorpyrifos on the expression of genes regulating neural progenitor identity, interneuron development and gliogenesis in developing rat hippocampus

  Walter Lichtensteiger, Catherine Bassetti-Gaille, Hubert Rehrauer, Jelena Kühn Georgijevic, Margret Schlumpf and Jesus A F Tresguerres

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• Mechanistic study of TEMPO-associated oxidative stress and genotoxicity

  Nan Mei, Xiaoqing Guo, Zuhong Zhang, Stacey L Dial, Vasily N Dobrovolsky, Si Chen and Lei Guo

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• Pharmacokinetic studies of protein drugs and assessment of their metabolism

  Eric Ezan

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• A 52-week safety study in Cynomolgus macaque for genetically modified rice expressing Cry1Ab/1Ac protein

  Qing Xia

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• Fifteen years′ experience treating cells with inorganic arsenic, a molecule able to induce genetic/ genomic instability and epigenetic changes even after its removal

  Fabio Caradonna

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• mRNA and miRNA expression patterns associated to pathways linked to metal mixture health effects

  Rojas E, Martinez Pacheco M, Rodriguez Sastre A and Valverde M

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• Computational prediction of interaction of lumefantrine with human topoisomerase II beta complexed to DNA

  Carmen Lucia Bassi Branco

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• Modulation of drug metabolizing enzymes by dietary doses of sulforaphane; role in its antihypertensive and anti-oxidant effect in spontaneously hypertensive rats

  Fawzy Elbarbry

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• Reactive oxygen species (ROS), oxidative stress and antioxidants: Enzyme mimetic selenium compounds as redox regulators

  Govindasamy Mugesh

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• Toxicology of polymeric biomaterials: A regulatory approach

  Mohanan P V

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• Dark purple glutinous rice Var. Luem Pua tea prevents DSS-induced colitis in mice

  J Sattayasai, K Thipart, N Techataweewan, W Mawthong, A N L Noenplab and N Sattayasai

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• A new pegylated recombinant E.coli L-asparaginase preparation (MC0609): Comparative pharmacokinetic/pharmacodynamic characterisation in Beagle dog and influence of anti-PEG IgM antibodies on the pharmacokinetics in B6D2F1 mice

  Poppenborg Sabine M

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• CCR-2 neutralization augments murine fresh bone marrow cells activation by S. aureus via ROS production and cytokine response

  Ajeya Nandi and Biswadev Bishayi

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• Changes in rat urinary heme metabolites predict the magnitude of the neurotoxic effects induced by a mixture of lead, arsenic and manganese

  Vanda Maria Falcao Espada Lopes de Andrade

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• X-ray fluorescence imaging in toxicology

  Yulia Pushkar

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• Effect of soy bean on histomorphometric parameters of stomach and biochemical factors of blood serum in animal model

  Simin Fazelipour, Zahra Tootian and Reyhaneh Hooshmand Abasi

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• From the lungs to the brain: The fantastic voyage of nanoparticles targeting beta-amyloid (Aβ)

  Giulio Sancini

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• BTEX is implicated in gasoline-induced oxidative stress in male albino Wistar rats

  Friday E Uboh, Saviour U Ufot and Uduak O Luke

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• Pre-activation of acetylcholine M3 receptor leads to cannabinoid type 1 receptors regulation: A new cross talk mechanism involving intracellular calcium mobilization in SH-SY5Y human neuroblastoma cells

  Pietro Marini

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• Determination of some blood hydrocarbons contents, oxidative stress markers and haematological indices of rats orally exposed to bonny light crude oil

  Saviour U Ufot, Friday E Uboh, Uduak O Luke and Patrick E Ebong

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• Nutraceuticals for hypertension care: A network based approach

  Matteo Micucci, Chiarini A and Budriesi R

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• Effects of lornoxicam and intravenous ibuprofen on erythrocyte deformability liver and renal blood flow in rats

  AySegul Kucuk, Hande Arpacı, Faruk Metin comu, Bahadır Kösem, Seyfi Kartal, Volkan Sıvgın, Huseyin Cihad Turgut, Muhammed Enes Aydın, Derya Sebile Koc and Mustafa Arslan

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• The effect of proton pump inhibitors on bone mineral density in rats

  Layla Ezzat Borham, Magda M Hagras, Altaf Abdulkhaliq and Mohammed Badawood

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• Beneficial effects of phloretin on oxidative and inflammatory reaction in rat model of cecal ligation and puncture induced sepsis

  Omid Sabzevari, M Aliomrani, M R Sepand, S Sabzevari, H Mirzaei and S Nekonam

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• Carbon monoxide modulates infection-induced proinflammatory cytokine milieu in human placenta

  Nazeeh Hanna

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• Flavonoid effects on antihypertensive pharmacological therapy: Modulation on lipid profile, inflammation and association of ACE (I/D) polymorphism in treatment response

  Marina M de Jesus Romero-Prado, Jiménez A, Miramontes M V and Curiel J

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• COX2 inhibition decreases ischemic damage to rat retina–function or structure

  Yoram Oron

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• Activation of the estrogen receptor by human serum extracts containing mixtures of perfluorinated alkyl acids from pregnant women′s serum

  Christian Bjerregaard-Olesen, Mandana Ghisari and Eva C Bonefeld-Jørgensen

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• Tamoxifen and its derivatives bind to and act at cannabinoid receptors CB1 and CB2 with high affinity

  Anna Radominska Pandya

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• Beta-blockers and sperm function

  Banihani S A

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• Individualised clinical toxicology: Physiological intermolecular modulation spectroscopy (PIMS), a technology to forsee drugs efficacy prior to administration

  Pierre Eftekhari

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• The utility of the minipig as an animal model in regulatory toxicology

  Gerd Bode

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• Dioxin-like POPs: Induced aryl hydrocarbon receptor transactivity in the Danish pregnant women

  Manhai Long and Eva C Bonefeld Jørgensen

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• Genotypic and phenotypic patterns of antimicrobial susceptibility of Helicobacter pylori strains among Egyptian patients

  Marwa Saad Fathi

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• Neuropharmacological and cochleotoxic effects of styrene can worsen the noise impact

  Pierre Campo and Ludivine Wathier

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• Proposed criteria for the evaluation of the scientific quality of mandatory rat and mouse feeding trials with whole food/feed derived from genetically modified plants

  Kerstin Schmidt, Janine Dohring, Christian Kohl, Maria Pla, Esther J. Kok, Debora C.M. Glandorf, Rene Custers, Hilko van der Voet, Jutta Sharbati, Ralf Einspanier, Dagmar Zeljenkova, Jana Tulinska, Armin Spok, Clare Alison, Dieter Schrenk, Annette Poting, Ralf Wilhelm, Joachim Schiemann, Pablo Ste

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• The effect of the first- and second-generation of antipsychotic drugs on SH-SY5Y brain cells and their toxicity

  Israa J Hakeem

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• Concomitant exposure of bacoside A and bromelain relieves dichlorvos toxicity in mice serum

  Sonam Agarwal and Renu Bist

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• Determination of chromium by ETAAS in hair and urine of tannery workers: The interest of alternative biological matrices

  Mohammed Riffi, Okacha Abdelmalek, Rania Abtroun, Mohammed Azzouz, Mohammed Reggabi and Barkahoum Alamir

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• Flexibility for automated cell based assays

  Lena Schober, Moriz Walter and Andrea Traube

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• Acute toxicity test of dichromate potassium (K2Cr2O7) in grey mullet (Mugil cephalus)

  Abdolreza Jahanbakhshi and Elnaz Erfanifar

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• Biological effects of nanoparticles on fish

  Zeinab H Arabeyyat

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• Anti-inflammatory effect and toxicology analysis of oral delivery quercetin nanosized emulsion in rats

  Gabriela Hadrich

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• Molecular nanoprobes and nanosensors: A new generation of biosensing nanoplatforms for toxicological and biomedical monitoring

  Tuan Vo Dinh

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