Translational Medicine
Open Access

Bronislaw L Slomiany

Biography

Bronislaw L Slomiany PhD Professor of Biochemistry and Molecular Biology and Medicine Professor of Oral Biology UMDNJNJ Medical School University of Medicine Dentistry of New Jersey 110 Bergen Street Newark NJ 07l032400 USA

Research Interest

Biology and function of alimentary tract secretions glycobiology of saliva and gastrointestinal tract mucus structure macromolecular organization and the role of mucus in mucosal defense alcohol abuse and oral mucosal and gastric injury molecular basis of mucosal tissue injury and repair pathogenic mechanisms of P gingivalis and H pylori action and mucosal defense; mucosal inflammatory responses to Pgingivalis and H pylori lipopolysaccharide co and post-translational processing of secretory glycoproteins signal transduction pathways affecting salivary and gastric mucin elaboration signal transduction and secretory control mechanisms role EGF and EGFR transactivation in secretory protein and glycoprotein processing; role of leptin and ghrelin in gastric and oral mucosal defense; extracellular matrix and their cell surface receptors (integrins) tooth-gingiva interaction; biochemistry of calcium channels modulators of oral and gastric epithelial secretory responses apoptosis, signal transduction endothelins, cPLA2 nitric oxide synthase NSAID and gastric and oral mucosal wound healing biochemical pharmacology of mucosal inflammatory responses