Journal of Developing Drugs
Open Access

Daniele Santini

Biography

Daniele Santini, Associate Professor, Department of Medical Oncology, Policlinico Universitario, ItalyUniversity “La Sapienza”, Rome, Italy. He graduated cum laude Medicine and Surgery degree from University La Sapienza, Rome, Italy, Graduated cum laude Resident-Specialty in Medical Oncology, PhD in Immunopharmacology.

Research Interest

Design and conduction of phase II-III clinical trials in solid tumours, Chemotherapy in gastrointestinal tumors, Molecular mechanisms on tumor progression, Molecular prognostic and predictive factors in gastrointestinal tumors, Role of bisphosphonates and emerging target therapies in Osteoncology (denosumab, Src inhibitors, Catepsine K inhibitors, Endothelin A inhibitors, Wnt/dkk agonist/antagonists, TGF beta inhibitors, etc.) Molecular Factors predictive of response to monoclonal antibodies and to tyrosine kinase inhibitors in solid tumors (EGFR inhibitors, Multitarget TKis, Antiangiogenic drugs, mTOR inhibitors, etc).