Biochemistry & Pharmacology: Open Access
Open Access

Filomena Conforti

Biography

Dr. Filomena Conforti working as a University Researcher in Department of Pharmaceutical Sciences, University of Calabria, Italy. Her research activity has been always focused on pharmaceutical biology topics, with particular attention to general and applied pharmacognosy matters. In particular, Filomena Conforti, since the beginning of her research career, has developed studies on phytochemical characterization of plant sources particularly interesting for healing fields developing extractive and analytical methods. For analytical characterizations, screening methods (TLC, HPTLC) and more exhaustive techniques (HPLC, GC, GC-MS, NMR) have been performed. To the extractive and analytical studies, particular emphasis has been devoted to the biological activities of natural chemicals. These investigations have been developed employing different cell lines and focused on the determination of their growth, morpho-functional aspects, cytotoxicity, enzyme inhibition (cholinesterase, amylase, glucosidase, nitric oxide synthase, lipase), phototoxicity and antioxidant activity of phytocomplexes, their fractions and isolated molecules. The research group to which Filomena Conforti takes part has proficiency to perform assays to test antiproliferative activity against different human tumor cell lines (liver, kidney, lung, melanoma, colorectal, prostate, breast). Along years, she has developed particular interest on ethnobotanical studies with particular attention to wild dietary plant in order to highlight the relationship between nutrition and health.

Research Interest

The research activity has been always focused on pharmaceutical biology topics, with particular attention to general and applied pharmacognosy matters. In particular, Filomena Conforti, since the beginning of her research career, has developed studies on phytochemical characterization of plant sources particularly interesting for healing fields developing extractive and analytical methods. For analytical characterizations, screening methods (TLC, HPTLC) and more exhaustive techniques (HPLC, GC, GC-MS, NMR) have been performed. To the extractive and analytical studies, particular emphasis has been devoted to the biological activities of natural chemicals. These investigations have been developed employing different cell lines and focused on the determination of their growth, morpho-functional aspects, cytotoxicity, enzyme inhibition (cholinesterase, amylase, glucosidase, nitric oxide synthase, lipase), phototoxicity and antioxidant activity of phytocomplexes, their fractions and isolated molecules. The research group to which Filomena Conforti takes part has proficiency to perform assays to test antiproliferative activity against different human tumor cell lines (liver, kidney, lung, melanoma, colorectal, prostate, breast). Along years, she has developed particular interest on ethnobotanical studies with particular attention to wild dietary plant in order to highlight the relationship between nutrition and health.