Anesthesia & Clinical Research
Open Access

Jae-Woo Lee

Biography

Dr Jae-Woo Lee has received his MD in the University of Chicago Pritzker School of Medicine.  He completed an anesthesiology residency at Beth Israel Deaconess Medical Center in Boston, MA, and a pediatric anesthesia fellowship in Boston Children´s Hospital.  Currently,  he is an Associate Professor In Residence within the Department of Anesthesiology in the University of California, San Francisco since 2002.

Research Interest

The main focus of Dr. Lee´s research is understanding the potential therapeutic role of allogeneic bone marrow derived human mesenchymal stem cells (MSC) in acute lung injury. To study this, he has developed three human models: (1) A fairly novel ex vivo perfused human lung injured by endotoxin and E. Coli pneumonia. (2 & 3) Primary cultures of both human alveolar epithelial type II cells and human lung microvascular endothelial cells grown on Transwell plates injured by an inflammatory insult.  Dr. Lee has authored multiple research articles/reviews/chapters on the role of mesenchymal stem cells in acute lung injury/acute respiratory distress syndrome.In collaboration with Dr. Michael Matthay, he is in the process of obtaining a FDA IND for a potential Phase II clinical trial of MSC in patients with ALI/ARDS.Dr. Lee´s research is currently funded by the NIH HLBI.   He has been a reviewer for grants for the National Institute of Health, American Heart Association and European Society of Critical Care Medicine.  He is a reviewer for manuscripts for multiple journals including Anesthesiology, Critical Care Medicine, American Journal of Physiology Lung Cell Molecular Physiology and the Proceedings of the American Thoracic Society.