Journal of Proteomics & Bioinformatics
Open Access

Kamalakannan Palanichamy

Biography

Dr. Palanichamy is working as an Assistant Professor in The The James Cancer Center / The Ohio State University Medical School, Columbus, OH, USA. Previously he worked as a Post-doctoral Research Associate, Massachusetts General Hospital / Harvard Medical School, Boston, Massachusetts, USA and Research Scientist, University of Wyoming, Laramie, USA. Dr. Palanichamy has secured many more grants like OSU-Startup grant, RC2 NCI-NIH grant, Colorado State University subcontract for in-vivo studies, R01 NCI-NIH grant – Sub-award from Dana-Farber Cancer Institute. So far he has published more than 35 papers in reputed international journals.

Research Interest

Dr. Palanichamy's research focus is to bridge the gap between basic and clinical research and explore transcriptomic, epigenetic, metabolomic, proteomic and genomic profiles in patient tumor biopsy samples to identify predictive and prognostic markers and validate therapeutic targets using pre-clinical models. He is also working to identify the underlying mechanisms of chemo and radiation resistance in treatment-refractory tumors by short-circuiting signal transduction pathways and determining the mutational status, gene and molecular signatures mediating treatment resistance. He has developed cancer stem cell models to investigate cancer stem cell biology via protein-protein interactions at translational and transcriptional levels. He's also conducting correlative biology studies in patient cohorts to determine whether a particular gene, protein, or metabolite contributes to progression free survival, overall survival, and toxicity.