Journal of Odontology
Open Access

Koichi Sakakura

Biography

2018 – Present President & Director, Laboratory for Head and Neck Immunology, Gunma ENT Clinic & Lab Following 4 projects have benn approved by our Institution Review Board: 1) “Immunological evaluations in various disesases using patients’ peripheral blood samples and clinical data, and immunological monitorings for immunotherapies” 2) “Immunohistochemical and genetic analyses for patients’ pathological samples and cytological sammples. 3) “Studies of anti-tumor response in autologous system using normal donors’ peripheral blood and and donor-derived primary cell culture” 4) “Hemodaynamic evalustions in cervical and vertebral arteries in vertigo, dizziness, tinnitus and hearinloss derived from insufficiency 2016 - 2017 Associate Professor, Lecuture, “Tumor microenvironment in patients with squamous cell carcinoma of the head and neck (SCCHN)” and “Local and systemic defects of immune cells in patients with SCCHN” Preceptor: Professor Kazuaki Chikamatsu, M.D., Ph.D. Department of Otolaryngology-Head and Neck Surgery, Gunma University Graduate School of Medical Science, Maebashi, Japan 2012 - 2016 Instructor, Assistant Professor, Clinical Fellow, “Tumor microenvironment in patients with squamous cell carcinoma of the head and neck (SCCHN)” and “Local and systemic defects of immune cells in patients with SCCHN” Preceptor: Professor Kazuaki Chikamatsu, M.D., Ph.D. Department of Otolaryngology-Head and Neck Surgery, Gunma University Graduate School of Medical Science, Maebashi, Japan 2010 - 2012 Head in Otolaryngology-Head and Neck Surgery, “Expressions of HLA class II antigen processing machineries in head and neck squamous carcinoma cells” As a principal investigator in Department of Otolaryngology-Head and Neck Surgery, National Hospital Organization Shizuoka Medical Center, Shizuoka, Japan 2008 - 2010 Postdoctoral Fellow in Immunology and Surgery, “HLA class II antigen processing machinery in cancer cells” and “Expression of proteoglycan tumor antigens on cancer cells” Preceptor: Professor Soldano Ferrone, M.D., Ph.D. and Assistant Professor XinHui Wang, Ph.D. Department of Immunology and Surgery, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA 2007 - 2008 Postdoctoral Fellow in Pathology, “T cell apoptosis induced by microvesicle secreted from head and neck cancer cells” and “Induction of tumor antigen-specific CTL response by in vitro stimulation using cDNA-transfected autologous dendritic cells” Preceptor: Professor Theresa L. Whiteside, Ph.D. and Professor Albert B. DeLeo, Ph.D. Department of Pathology, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA 2002 - 2007 Clinical Fellow, Research Assistant and Graduate Student, “CD8/CD4+ T cell responses against p53 epitopes in patients with squamous cell carcinoma of the head and neck (SCCHN)” and “Local and systemic defects of immune cells in patients with SCCHN” Preceptor: Assistant Professor Kazuaki Chikamatsu, M.D., Ph.D. Department of Otolaryngology-Head and Neck Surgery, Gunma University Graduate School of Medical Science, Maebashi, Japan 2001 - 2005 Graduate Student, “Vestibular Evoked Myogenic Potential in rat and human” Preceptor: Professor Nobuhiko Furuya, M.D., Ph.D. Department of Otolaryngology-Head and Neck Surgery, Gunma University Graduate School of Medical Science, Maebashi, Japan 2000 - 2002 Clinical Fellow, “Epidemic otitis media by Penicillin Resistant Streptococcus pneumoniae and Beta-lactamase Negative Ampicillin Resistant Haemophilus influenzae in Japan” Preceptor: Head Tetsuo Takegoshi, M.D., Ph.D. Department of Otolaryngology, Social Insurance Gunma Chuo General Hospital, Maebashi, Japan

Research Interest

Otorhinolaryngology, head and neck surgery, nutrition, dysphagia and swallowing function, thyroid disease, pediatric surgery, and oriental medicine.