Journal of Nutrition & Food Sciences
Open Access

Kyu Lim

Biography

Dr. Kyu Lim is currently full Professor (1996- ), Department of Biochemistry, Chungnam National University School of Medicine, Korea. He graduated from Yeongnam University College of Pharmacy in 1975, received his Ph.D. from same University (Biochemistry: Enzymology) in 1987 and undertook his Postdoctoral training with Dr. Chi-Bom Chae in the Department of Biochemistry and Biophysics, University of North Carolina School of Medicine at Chapel Hill (1988-1990; Gene regulation) and Visiting Associate Professor in the same University (1991). He also worked as Visiting Professor on Inflammation and Cancer (including Omega-3 fatty acid and Cancer etc.) with Dr. Tong Wu, Department of Pathology, University of Pittsburgh School of Medicine (2005-2007). Dr. Lim was Chair in his Department (1994-2005) and Director, Cancer Research Institute in Chungnam National University (2009-2011). Recently, he was a Chair in Autophagy Reserch Session of KSBMB (2013-2014). Dr. Lim is one of the leading scientists in the field of a research on the Omega-3 fatty acids and Cancer. He has worked to identify novel molecular mechanisms of anticancer action of omega-3 fatty acids in several cancers since 2005. For example, he found that omega-3 fatty acids inhibits wnt/beta-catenin signaling and Cox-2 (Cancer Res, 2008; Mol Cancer Ther, 2009; Pancreatology, 2011 etc.), and induces cell death through autophagy (Autophagy, 2011; BioMed Res Intl, 2013 etc.). Additionall, he found that DHA degrades HPV E6/E7 oncoprotein through Ubiquitin/proteasome activation (Cell death and Disease, 2014). He has also researched on Inflammation and Cancer, Regulation of gene expression on metastasis- and angiogenesis-related proteins. He also published several books’ chapter and reviews on Omega-3 Fatty acids and Cancer. In 2010, he organized Korea-EU International Forum on Omega-3 fatty acids and Cancer. Dr. Lim has been invited to speak more than 70 times from International and domestic Laboratories.

Research Interest

I have worked to identify novel molecular mechanisms of anticancer action of omega-3 fatty acids in several cancers, especially cervical cancer since 2005. For example, we found that omega-3 fatty acids inhibits wnt/beta-catenin signaling and Cox-2 (Cancer Res, 2008; Mol Cancer Ther, 2009; Pancreatology, 2011 etc.), and induces cell death through autophagy (Autophagy, 2011; BioMed Res Intl, 2013 etc.). Additionall, I found that DHA degrades HPV E6/E7 oncoprotein through Ubiquitin/proteasome activation (Cell death and Disease, 2014). I have also researched on Inflammation and Cancer, Regulation of gene expression on metastasis- and angiogenesis-related proteins.