Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biol
Open Access

Marek Malecki

Biography

He earned MD degree at the Medical Academy, Poznan followed by Residency/Fellowship in Molecular Medicine in Rigshospitalet, Copenhagen. He earned PhD at the Polish Academy of Sciences, Warsaw followed by the postdoctoral fellowships in molecular biology at the Austrian Academy of Sciences, Salzburg, ETH, Zurich, Utrecht University, Utrecht, Cancer Center, Vienna, Cancer Center, Amsterdam, Biozentrum, Basel. He is currently Associate Professor of Genetics, Genomics, and Gene Therapy at the Western University, Pomona, CA and President of Phoenix Biomolecular Engineering Foundation, San Francisco, CA.

Marek Malecki MD PhD developed a cancer suicide gene therapy. It was initially developed for ovarian cancers as the means of targeted elimination of cancer cells, while retaining healthy cells intact. This is the best way to retain women’s fertility in cases of cancer. It is based upon the synthetic scFv and probes, which he invented and patented (USPTO and WIPO). A big role in this gene therapy is played by the nuclear routing network, which he discovered during his tenure at the NIH, National Biotechnology Resource. He also developed the unique protocols of cryo-immobilization of living cells which retain their high viability.

Research Interest

Cancer of ovaries, cancer of testes, cancer stem cells (CSC), circulating tumor cells (CTCs), genetic disorders, iatrogenic genetic mutations, gene therapy, targeted gene delivery, site specific recombination, fertility sparing therapy, biobanking, in vitro fertilization.