Journal of Glycomics & Lipidomics
Open Access

Rafat Ali Siddiqui

Biography

Rafat Siddiqui have earned my BSc 1978 MSc 1980 degrees in Biochemistry with First Class first Position from the University of Karachi, Karachi, Pakistan. I obtained my PhD in 1988 from the Australian National University Canberra Australia During my PhD I investigated the metabolic basis of cancer cachexia under the supervision of Professor John F Williams who is famous for his research on the pentose phosphate pathway I served as a postdoctoral fellow 19871989 in Dr Stuart McCutcheons Currently Vice Chancellor Auckland University New Zealand laboratory at Massey University Palmerton North New Zealand I immigrated to America in 1989 on an invitation from Dr John Exton on a Howard Hughes Medical Institute HHMI fellowship at Vanderbilt University Medical Center Vanderbilt University Nashville Tennessee I started my research work in the Bone Marrow Transplant Research Laboratory at Methodist Hospital in 1993 where I established my independent research laboratory in 1999 At present I am a Senior Investigator and the Director of the Cellular Biochemistry Research Laboratory at the Methodist Research Institute I also have an adjunct Professor appointment in the Department of Biology Indiana University, Purdue University Department of Medicine Indiana University Medical School Indianapolis IndianaDuring the course of my scientific career I have developed broad expertise in the life science research area However my research is primarily focused to investigate how dietary fats impact diseases particular cardiovascular and cancer I have developed a very successful research program at the Methodist Research Institute in the area of molecular nutrition In the cardiovascular area I am studying how omega3 fatty acids and trans fatty acids effect vascular remodeling and functions My work published in this area was included in the top 5 articles in the area of cardiovascular research for the Annual Bibliography of Significant Advances in Dietary Supplement Research 2006 Office of the Dietary Supplements National Institute of Health Bethesda Maryland Similarly my notable contribution in the cancer area is the development of fatty acidspolyphenol conjugates with anticancer properties This work has also received a worldwide attention.

Research Interest

My research interest is to understand the mechanisms by which lipid and lipid-derived mediators impact the development cardiovascular disease and cancer, and to develop new therapies and dietary recommendations to improve outcomes.