Journal of Cell Signaling
Open Access

Wei Zhang

Biography

I obtained my PhD in Dr. Daniel Durocher lab at the Lunenfeld Institute of Mount Sinai Hospital, and Department of Molecular Genetics at University of Toronto. With Dan I learned about using molecular biology, genetics, and cell biology to understand genome stability, DNA repair, and telomere biology. Meanwhile I graduated from a two-year radiation medicine program (EIRR21, now STARS21) in the Department of Radiation Oncology at University of Toronto. With a CIHR fellowship and later a Mitacs Elevate Fellowship I further conducted postdoctoral work in the labs of Drs. Sachdev Sidhu and Jason Moffat in the Donnelly Centre at University of Toronto. I learned from Dev and Jason how to “modulate” cell signalling using protein engineering, synthetic biology, and systems biology approaches. Here in my own lab I propose to combine the expertise I gained from my PhD and Postdoc studies to further understand and modulate DNA damage responses for novel cancer therapeutics.

Research Interest

Synthetic Biology | Biomolecular Engineering | Protein Design | Protein-Protein Interactions | Protein
Post-translational Modifications | DNA Damage Response | Cancer Therapeutics