Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biol
Open Access

Yimin Shu

Biography

Dr. Shu is a board certified high-complexity clinical laboratory director (HCLD) in the disciplines of Embryology and Andrology by American Board of Bioanalysis. He is a senior research scientist at Stanford University and also the embryology laboratory director of Fertility Associates of Memphis, TN. Dr. Shu has been working in the field of assisted reproductive technology for more than 12 years. His extensive experience covers all aspects of embryology and andrology.
Dr. Shu has been actively involved in both clinical and basic research in the field of reproductive biology and has authored over 30 articles in peer-reviewed scientific journals. He has been selected as a peer-reviewer by several journals in the filed of reproductive biology and infertility and is now serving as a member of editorial board of Human Reproduction. His current research is focused on early embryonic development, in vitro maturation, fertility cryopreservation, nuclear transfer, and stem cell biology. 

Research Interest

Embryology: In vitro fertilization, Oocyte and embryo culture, Micromanipulation (intracytoplasmic sperm injection, assisted hatching), Evaluation and selection of embryos for transfer, Immunosurgery, Andrology:  Semen analysis, Semen preparation for assisted reproductive technology, Sperm identification from percutaneous sperm aspiration and testicular aspiration/biopsy
Preimplantation genetic diagnosis:  Embryo biopsy (cleavage stage and trophectoderm biopsy),  blastomere and trophectoderm fixation 
Fertility cryopreservation:   Gametes (oocyte and sperm) and embryo cryopreservation (slow freezing and vitrification)
Somatic Cell nuclear transfer: Derivation of embryonic stem cell line from blastocysts, Passaging of  human embryonic stem cell lines, Enucleation, nuclear transfer, electrofusion of a donor nucleus and an enucleated oocyte, and embryonic stem cell, chromosome transfer between oocytes and zygotes
Administration: IVF Lab QA/QC, proficiency testing, prepare for CAP and FDA inspection, train new embryologist, supervise staff embryologist, good organizational and inter-personnel skills
Molecular Biology: DNA and RNA extraction and amplification, RT-PCR, Real-time PCR, DNA Microarray, QABD, Whole genome amplification (WGA), Proteomics,Immunofluorence for oocytes and embryos, Confocal microscope imaging  
Stem Cell  Biology and Nuclear Transfer: Derivation of embryonic stem cell line from blastocysts, Passaging of  human embryonic stem cell lines, Enucleation, nuclear transfer, electrofusion of a donor nucleus and an enucleated oocyte, and embryonic stem cell, chromosome transfer between oocytes and zygotes
Reproductive Biology: Detection of spindle by using non-invasive OoSight system in oocytes and somatic cells, synchronization of cell cycles by chemical treatment, In vitro human oocyte maturation, Artificial oocyte activation, Fluorescence assay of gap junction-mediated communication, Identification of embryos with superior developmental potential, somatic cell reprogramming