Journal of Clinical & Experimental Dermatology Research

Journal of Clinical & Experimental Dermatology Research
Open Access

ISSN: 2155-9554

+44 1478 350008

Clinical image - (2019)Volume 10, Issue 6

A Giant Buschke-Löwenstein Tumor

Sara Mai1*, Salima Baya2, Safae Maouini1, Kaoutar Znati3, Jawad Hafidi2, Abdellah Abbassi2 and Karima Senouchi1
 
*Correspondence: Sara Mai, Department of Dermatology, University Hospital Ibn Siba, Rabat, Morocco, Tel: +212625104836, Email:

Author info »

Abstract

A 70-year-old man with no notable medical history presented to our department with a huge tumor on his pubic area that had been evolving for over 20 years causing itching and foul smelling discharge. Physical examination revealed a cauliflower-like voluminous tumor on the patient’s pubis with extension to the penoscrotal area and the lower abdomen (Figure 1).

Clinical Image

A 70-year-old man with no notable medical history presented to our department with a huge tumor on his pubic area that had been evolving for over 20 years causing itching and foul smelling discharge. Physical examination revealed a cauliflower-like voluminous tumor on the patient’s pubis with extension to the penoscrotal area and the lower abdomen (Figure 1). A giant condyloma acuminate was suspected and extensive surgical excision was performed. Histopathological examination revealed hyperkeratosis, acanthosis, marked papillomatosis and koilocytes; confirming the diagnosis of Buschke-Löwenstein tumor (Figure 2). There were no features of malignant transformation [1-3].

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Figure 1. Patient’s pubis with extension to the penoscrotal area and the lower abdomen.

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Figure 2. Diagnosis of Buschke-Löwenstein tumor.

Buschke-Löwenstein tumor or giant condyloma acuminatum is a rare sexually transmitted disease, caused by human papillomavirus; genotypes 6 and 11 in most cases. It’s incidence of about 0.1% in the general population, predominantly young men. Clinically it presents as a large, cauliflower-like tumor with papillomatous or verrucous surface. Radical excision of the entire lesion with histopathological examination of the whole lesions is recommended to confirm the diagnosis and detect a malignant transformation. Post-operative surveillance is necessary to identify potential recurrences [4,5].

Funding

Nil.

Conflict of Interest

The authors declare that they have no competing interest.

References

  1. Lévy A, Lebbe C. Buschke-Löwenstein tumour: diagnosis and treatment. Ann Urol (Paris) 2006;40:175-178.
  2. Chu QD, Vezeridis MP, Libbey NP, Wanebo HJ. Giant condyloma acuminatum (Buschke-Lowenstein tumor) of the anorectal and perianal regions. Analysis of 42 cases. Dis Colon Rectum. 1994;37:950-957.
  3. Heinzerling LM, Kempf W, Kamarashev J, Hafner J, Nestle FO. Treatment of verrucous carcinoma with imiquimod and CO2 laser ablation. Dermatology. 2003;207:119-122.
  4. Creasman C, Haas PA, Fox TA Jr, Balazs M. Malignant transformation of anorectal giant condyloma acuminatum (Buschke-Lowenstein tumor) Dis Colon Rectum. 1989;32:481-487.
  5. Geusau A, Heinz-Peer G, Volc-Platzer B, Stingl G, Kirnbauer R. Regression of deeply infiltrating giant condyloma (Buschke-Löwenstein tumor) following long-term intralesional interferon alfa therapy. Arch Dermatol. 2000;136:707-710.

Author Info

Sara Mai1*, Salima Baya2, Safae Maouini1, Kaoutar Znati3, Jawad Hafidi2, Abdellah Abbassi2 and Karima Senouchi1
 
1Department of Dermatology, University Hospital Ibn Siba, Rabat, Morocco
2Department of Plastic Surgery, University Hospital Ibn Siba, Rabat, Morocco
3Department of Histopathology, University Hospital Ibn Siba, Rabat, Morocco
 

Citation: Mai S, Baya S, Maouni S, Znati K, Hafidi J, Abbassi A, et al (2019). A Giant Buschke-Löwenstein Tumor. J Clin Exp Dermatol Res. 10: 512. DOI: 10.35248/2155-9554.19.10.512

Received: 01-Nov-2019 Accepted: 14-Nov-2019 Published: 20-Nov-2019

Copyright: © 2019 Mai S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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