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Editorial - (2021)Volume 9, Issue 5
Carcinoid tumors are a type of slow-growing cancer that can arise in several places throughout your body. Carcinoid tumors, which are one subset of tumors called neuroendocrine tumors, usually begin in the digestive tract (stomach, appendix, small intestine, colon, rectum) or in the lungs. Carcinoid tumors often don't cause signs and symptoms until late in the disease. Carcinoid tumors can produce and release hormones into your body that cause signs and symptoms such as diarrhea or skin flushing.
It's not clear what causes carcinoid tumors. In general, cancer occurs when a cell develops mutations in its DNA. The mutations allow the cell to continue growing and dividing when healthy cells would normally die. The accumulating cells form a tumor. Cancer cells can invade nearby healthy tissue and spread to other parts of the body.
Doctors don't know what causes the mutations that can lead to carcinoid tumors. But they know that carcinoid tumors develop in neuroendocrine cells. Neuroendocrine cells are found in various organs throughout the body. They perform some nerve cell functions and some hormone-producing endocrine cell functions. Some hormones that are produced by neuroendocrine cells are histamine, insulin and serotonin.
Older age older adults are more likely to be diagnosed with a carcinoid tumor than are younger people or children.
Sex women are more likely than men to develop carcinoid tumors.
Family history of multiple endocrine neoplasia, type 1 (MEN 1), increases the risk of carcinoid tumors. In people with MEN 1 multiple tumors occur in glands of the endocrine system.
Carcinoid syndrome causes redness or a feeling of warmth in your face and neck (skin flushing), chronic diarrhea, and difficulty breathing, among other signs and symptoms.
Carcinoid heart disease may secrete hormones that can cause thickening of the lining of heart chambers, valves and blood vessels. This can lead to leaky heart valves and heart failure that may require valve-replacement surgery. Carcinoid heart disease can usually be controlled with medications.
Cushing syndrome lung carcinoid tumor can produce an excess of a hormone that can cause your body to produce too much of the hormone cortisol.
When carcinoid tumors form on cells that make hormones, the tumors can start to make hormone-like substances of their own. This can cause a variety of symptoms, depending on where this is going on.
If you have a lung carcinoid tumor, you might get symptoms like a cough, and you sometimes might cough up some bloody mucus. You also might hear a whistling sound while you breathe, called wheezing. When you have this type of cancer for many years, you might get a condition called carcinoid syndrome. It's a group of symptoms that start when the tumors release certain hormones into your bloodstream.
Talk to your doctor about the treatment plan that's best for you. And don't neglect your emotional needs while this is going on. Tap into your network of friends and relatives to get support as you take care of your health. See if you can join a support group near you where you can talk to people who know what it's like to go through treatment and recovery.
Received: 08-May-2021 Accepted: 15-May-2021 Published: 22-May-2021 , DOI: 10.35248/2329-6917.21.9.e122
Copyright: This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.