Abstract

Introduction: The term chemobrain is a short name for chemotherapy associated cognitive dysfunction. So far there is neither clear definition of the term chemobrain nor its epidemiology or pathogenesis are known and there have been no prospective studies addressing this condition. Method: Here, in this short review we provide an overview on the most recent findings of chemobrain pathogenesis, prevention and available treatment. We take a novel perspective on the role of blood-brain barrier in the development of chemotherapy associated cognitive dysfunction and discus briefly new and upcoming treatment.