Pancreatic Disorders & Therapy

Pancreatic Disorders & Therapy
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Clinical image - (2021)Volume 11, Issue 2

Insulimona Patient with Acanthosis Nigricans

Samuel Srinivasan*
 
*Correspondence: Samuel Srinivasan, Scheie Eye Institute, Department of Diabetes, Chellaram Hospitals, Pune, India, Email:

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Description

A 46-year-old female patient analyzed to have insulinoma with hyperinsulinemia had acanthosis nigricans of grade 2 in the neck (Figure 1). She has given rehashed scenes of conduct changes diaphoresis, migraine, and disarray for a very long time, which bit by bit advanced in recurrence to such an extent that the patient had indications consistently. She prior gave social changes to a therapist and was recommended antipsychotic prescription [1-3]. She had an unconstrained hypoglycemic scene that mitigated on devouring food. She had a background marked by obscuring of skin with weight acquire, was large with a weight file (BMI) of 41.7 kg/m2 , and a circulatory strain of 167/80 mmHg. The laboratory manifestations like immunohistochemistry and histological tests that confirmed insulinoma, after an year there is a relapse of her acanthosis nigricans [4-7] (Figure 2).

pancreatic-nigricans

Figure 1: Patient with Acanthosis Nigricans.

pancreatic-surgery

Figure 2: Patient after the surgery.

References

  1. Pfeifer SL, Wilson RM, Gawkrodger DJ. Clearance of acanthosis nigricans associated with the HAIR-AN syndrome after partial pancreatectomy: An 11 year follow-up. Postgrad Med. 1999;75:421-422.
  2. Phiske MM. An approach to acanthosis nigricans. Ind Dermatol Online J. 2014;5:239e249.
  3. Cox AR, Ferner RE. Prescribing errors in diabetes. Br J Diabetes Vasc Dis. 2009;9:84–88.
  4. Ito T, Tanaka M, Sasano H, Osamura YR, Sasaki I, Kimura W, et al. Preliminary results of a Japanese nationwide survey of neuroendocrine gastrointestinal tumors. J Gastroenterol. 2007; 42: 497-500.
  5. Zhu L, Domenico DR, Howard JM. Metastatic pancreatic neuroendocrine carcinoma causing Cushing’s syndrome. ACTH secretion by metastases 3 years after resection of nonfunctioning primary cancer. Int J Pancreatol. 1996; 19: 205-208.
  6. Venook AP. Embolization and chemoembolization therapy for neuroendocrine tumors. Curr Opin Oncol. 1999; 11: 38-41.
  7. Honda Y, Iyama K. Malignant adenomyoepithelioma of the breast combined with invasive lobular carcinoma. Pathol Int. 2009; 59: 179-184.

Author Info

Samuel Srinivasan*
 
Department of Diabetes, Chellaram Hospitals, Pune, India
 

Citation: Srinivasan S (2021) Insulimona Patient with Acanthosis Nigricans. Pancreat Disord Ther. 11: 222.

Received: 11-Jun-2021 Accepted: 25-Jun-2021 Published: 02-Jul-2021

Copyright: © 2021 Srinivasan S. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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