Journal of Nanomedicine & Biotherapeutic Discovery

Journal of Nanomedicine & Biotherapeutic Discovery
Open Access

ISSN: 2155-983X

+44 1300 500008

Editorial - (2011) Volume 1, Issue 1

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Nanomedicine-based Synthetic Biology

Yeoheung Yun1*, Laura Conforti2, Perpetua Muganda1 and Jagannathan Sankar1
1Engineering Research Center, North Carolina A&T State University, Greensboro, NC, USA, E-mail: laura@gmail.com
2College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA, E-mail: laura@gmail.com
*Corresponding Author: Yeoheung Yun, Engineering Research Centre, North Carolina A&T State University, Greensboro, NC, USA Email:

Abstract

Understanding the disease mechanisms of complex biological systems is still a significant challenge. Biological systems consist of hundreds of thousands of genes and proteins which are very hard to identify and whose behavior is difficult to correlate, understand and predict. The traditional hypothesis-driven basic research aims to study a certain gene/protein or a certain signalling pathway by taking a biological system apart in such a way that is strictly dependent on the scientific method applied. However, this approach cannot provide a systemic information broad enough to predict the complex dynamic consequences of altered gene and protein expression and, ultimately, drug effectiveness. Synthetic biology, in combination to classical methods, is recently emerging as an alternative method.

Acknowledgements

This research was supported by the Business for International Cooperative Research and Development between Industry, Academy and Research Institute funded by the Korean Small and Medium Business Administration (Project no. 00042172-1).

References

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  2. Mitchel J Doktycz and Michael L Simpson (2007) Nano-enabled synthetic biology, Mol Syst Biol. Vol.3, 25.
  3. Eric Young and Hal Alper (2010) Synthetic Biology: tools to design, build, and optimize cellular processes, J Biomed Biotechnol 2010:12.
  4. Weber W, Fussenegger M (2009) The impact of synthetic biology on drug discovery. Drug Discov Today.14:956-963.
Citation: Yun Y, Conforti L, Muganda P, Sankar J (2011) Nanomedicine-based Synthetic Biology. J Nanomedic Biotherapeu Discover 1:102e.

Copyright: © 2011 Yun Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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