Journal of Communication Disorders, Deaf Studies & Hearing Aids
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Nicotine-Induced Hearing Loss among Young Saudi Male Students

Wahab O. Owolawi^1* and Vincent A. Adekoya^{2 *}Correspondence: Dr. Wahab O. Owolawi, Department of Rehabilitation Science, King saud university, Riyadh, Saudi Arabia, Email:

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Introduction

According to Dawes smoking may represent a significant cause of hearing loss worldwide [1]. It is found that the more packets one smokes per week and the longer one smokes, the greater the risk of hearing damage. Over 164,000 adults were studied in the UK and finding revealed that those who currently smoke have a 15.1 percentage (15.1%) higher chance of hearing loss. In the same study, it was opined that second-hand smokers or so-called passive smokers equally stand the risk, especially, if exposed for more than 10 hours per week may have a 40% risk of hearing loss.

Literature on smoking and its effect have long established that adolescents and children of mothers who smoked during pregnancy are vulnerable. High incidence of otitis media in young children whose parents smoke have equally been documented in comparison to those whose parents are nonsmokers. This incidence of otitis media may not be unrelated to irritation of the Eustachian tube and mucosa of the middle ear.

Blood flow and oxygen are both extremely important in maintaining healthy hair cells in the cochlea but nicotine and carbon monoxide contained in cigarette have been implicated in the depletion of oxygen levels and constriction of blood vessels all over the body including the auditory system.

Simply put, nicotine is classified to be ototoxic. In addition, nicotine can cause tinnitus, dizziness and vertigo. According to a blog, bloomhearing, nicotine interfers with neurotransmitters in the auditory nerve [2]. Neurotransmitters, are responsible for telling the brain which sound an individual is hearing. This interference can cause tinnitus, dizziness and vertigo.

Debbie clearly states that nicotine interferes with neurotransmitters in the auditory nerve which are responsible for telling the brains which sound you are hearing [3]. Further to this, it’s also stated that smoking increases not only sensitivity to loud noises which may result in a smoker developing noiseinduced hearing loss, nicotine also damages cells in the body turning them into free radicals that are capable of damaging the DNA and causing diseases.

Katbamna has cited evidence of nicotine effect on neurotransmitters [4]. According to this author, when smoking combines with factors of noise exposure and age, a serious and irreversible hearing loss may be expected. Pouryaghoub corroborated this finding in their study where it’s reported that smoking and occupational noise interaction exacerbates hearing loss [5]. Although in two other independent studies, Mizoue and Palmer smoking is said to independently affect hearing loss [6,7].

In a separate study on smoking and coronary artery diseases, Al- Nozha found a correlation between smoking and coronary artery diseases [8]. It is a well-known fact that good circulation cannot be under-played in the maintenance of good hearing health. Inadequate blood flow may be detrimental and traumatic to the function of the cochlea.

Case Study

Subjects

Forty (40) healthy male students of age range of 18-24 and a mean of 21 were recruited to participate in this study. Seven (7) chronic smokers and thirty-three (33) non-smokers volunteered to participate in the study. Each subject was given a questionnaire made-up of twenty four items (Audiological Profile of Chronic Cigarette Smokers Questionnaire–APCCSQ) to fill. Each questionnaire contained biography information, smoking or non-smoking status, average sticks of cigarette smoked per day, duration of smoking, pastime activities such as listening to loud music, ear/hearing health history including past incidence of tinnitus and vertigo, general medical/drug history, knowledge of effect of nicotine on health and hearing in particular.

Inclusion/exclusion criteria

Those with minimum of three years history of smoking and average of ten (10) sticks of cigarette per day were recruited into the study. Those who reported past history of ear diseases, surgery, listening to loud music or exposure to any high decibel noise level as well as those on medications that may have a potential of compromising the auditory system were excluded from participation.

Test protocol

Each participant was subject to otologic examination using Welch Allyn Digital Macroview video otoscope, pure tone audiometric test using GSI 61 calibrated to ANSI (2004) specification. Participants were also examined using an up-todate calibrated GSI-39 Autotymp at 226 Hz probe tone to assess middle ear function.

Those found with occluding cerumen within the ear canals and abnormal tympanometric findings taking into account James Jerger’s classifications of ‘A’ (normal) ‘B’, ‘C’, ‘As’ and ‘Ad’ for abnormal were excluded from the study.

Pure tone audiometric test was carried out using a baseline of <25 dBHL as normal threshold across frequencies 0.5-8 KHz in a sound-proof audiometric room of the college of applied medical sciences of King Saud University.

Results

Audiometric pattern of Smokers (S) and Non-Smokers (NS) found to be generally within normal limits of 25 dBHL but in threshold sensitivity across board non-smokers presented a better hearing compared to smokers (0-10 dBHL; 10-25 dBHL) (Tables 1 and 2).

Table 1: Average thresholds air conduction and bone conduction in smokers.

Table 2: Average thresholds air conduction and bone conduction in non-smokers.

It is observed that audiometric pattern showed elevated thresholds for smokers at higher frequencies (15 dBHL at 4 KHz, 25 dBHL at 8 KHz; 15 dBHL at 4 KHz and 25 dBHL at 8 KHz) on right and left ears respectively. Non-smokers hearing sensitivity at higher frequencies of 4 KHz and 8 KHz showed a threshold of less than <10 dBHL at all test frequencies with the exception of 8 KHz on the right ear (Figure 1).

Figure 1: Audiometric bar chart of smokers and non-smokers.

Discussion

Physiologically, it may not be out of place to assume that the base of the cochlea in smokers may be under some sort of metabolic stress thereby in a state of gradual compromise. It is clinically common to observe higher frequency hearing loss in cases of ototoxicity of which nicotine is so classified. This observation may be suggestive of gradual loss of hearing sensitivity at the basal end of the cochlea. The finding is found to be in consonance with other studies [1,9-11].

Meanwhile, audiometric threshold elevation as documented in other studies on smokers lends some measure of credence to the findings of this audiometric study. Chang discovered in their study that cigarette smoking increases hearing impairment and that it equally affects hearing thresholds [12]. Kumar found a similar correlation in their hospital based study on effect of smoking on the hearing status [13].

Paschoal and de Azevedo reported that smoking has an adverse effect on the auditory system on the basis of high frequency audiometric and oto-acoustic studies conducted on a sample of one hundred and forty-four (144) gender-mix adults [14]. Nair opined that pathological auditory involvement was clearly evident in smokers as an indication of reduced hearing sensitivity in the higher frequencies pure tone audiometric test of smokers [15]. These authors also reported implication of outer hair cells of the cochlea in a Distortion Product Oto- Acoustic Emission (DPOAE) findings.

Ohgami found a correlation between light smokers and high frequency hearing loss in young adults [9]. In an unpublished study in a Saudi Population Ahmed found that without the noise component, effect of smoking is negative [16]. This finding has been debunked by some other studies such as Mazoue and Palmer publications [6,7]. In this study, all participants reported zero exposure to noise yet an indication of minimal but audiometrically significant elevated thresholds on the higher frequencies among smokers was found in comparison to those of non-smokers who can be classified ‘super-normal’ in hearing. All sampled subjects claimed knowledge of health hazards of smoking but higher percentage (>70%) did not link smoking to any possible negative hearing impact [17,18].

Conclusion

There’s no conflicting findings on smoking and effects on hearing in several publications, it may however sound expedient for audiology clinicians to consider among other things an addition of tobacco use in the case history of adult patients. While it is agreeable that this study has very few sample subjects on smoking and lack statistical analysis of finding, simple audiometric pattern tend to loosely indicate a correlation between smoking and hearing effect.

It may equally be essential to include in general community hearing screening programme examination of people who admit to long-term cigarette smoking and also extend to them the privilege of periodic auditory sensitivity test, perhaps on a biannual basis while those with combined noise exposure and smoking should be scheduled for quarterly appointment or less.

Counselling sessions in audiologic practice must equally view the need for transmission of adequate information on the effect of smoking not only on general health but also on the auditory system to both chronic and passive (secondary) smokers.

However, in a future study objective test instruments such as diagnostic Oto-Acoustic Emission (OAE), Auditory Brain-stem Response (ABR) which are not included in this study due to their non-availability, must be considered. The good news, however, is the conclusion drawn by Hu which indicate that excess risk of hearing loss associated with smoking disappears in a relatively short period after quitting. Dawes study corroborates this finding. In a similar gender-based study Wang, states that after adjusting for covariates it was found that current smokers and past smokers middle-aged males had a significantly higher prevalence of speech-frequency loss and high frequency hearing loss. Slightly elevated high frequency threshold in this study among smokers tend to be in resonance with Wang finding.

References

1. Dawes P, Cruickshanks KJ, Moore DR, Edmondson-Jones M, McCormack A, Fortnum H, et al. Cigarette smoking, passive smoking, alcohol consumption, and hearing loss. J Assoc Res Otolaryngol. 2014;15(4):663-674
2. Smoking Your Ears Away: The Impact of Cigarettes on Hearing Loss & Tinnitus. Bloom Hearing Specialists. 2013.
3. Clason D. The dangerous link between smoking and hearing loss. Heathy Hearing. 2017.
4. Bharti K. Effects of cigarette smoking on distortion product oto-acoustic emissions. J Am Acad Audiol. 2007;18(2):665-674.
5. Pouryaghoub G, Mehrdad R, Mohammadi S. The interaction of smoking and the occupational noise exposure on the hearing loss: A crossectional study. BMC Public Health. 2007;7(1):137.
6. Mizoue T, Miyamoto T, Shimizu T. The combined effect of smoking and the occupational exposure to noise on the hearing loss in steel factory workers. Occup Environ Med. 2003;60(1):56–59.
7. Palmer KT, Griffin MJ, Syddall HE, Coggon D. Cigarette smoking, the occupational exposure to noise, and the self-reported hearing difficulties. Occup Environ Med. 2004;61(4):340–344.
8. Al-Nozha MM, Al-Mazrou YY, Arafah MR, Al-Maatouq MA, Khalil MZ, Khan NB, et al. Smoking in Saudi Arabia and its relation to coronary artery disease. J Saudi Heart Assoc. 2009;21(3):169–176.
9. Ohgami N, Kondo T, Kato M. The effects of light smoking on extra-high frequency auditory thresholds in young adults. Toxicol Ind Health. 2011;27(2):143-147.
10. Cruickshanks KJ, Klein BE, Klein R, Nondahl DM, Tweed TS, Wiley TL. Cigarette smoking and hearing loss: The epidemiology of hearing loss study. JAMA. 1998;279(21):1715-1719.
11. Hyun SJ, Sun SC, Choong-Ryeol L, Cheol-In Y, Hun L, Yangho K. Relationship of cigarette smoking and hearing loss in workers exposed to occupational noise. Ann Occup Environ Med. 2013;25(1):8.
12. Chang J, Ryou N, Jun HJ, Hwang SY, Song JJ, Chae SW. Effect of cigarette smoking and passive smoking on hearing impairment: Data from a population-based study. PloS one. 2016;11(1):e0146608.
13. Adesh K, Rajiv G, Sangeeta S, Abrar H and Asif K. The Effect of smoking on the hearing status-A hospital based study. 2013;7(2):210–214.
14. Pamplona PC, Frasson DM. Cigarette smoking as a risk factor for auditory problems. 2009;75(6):893-902.
15. Nair PG, Jestina JJ, Unnikrishnan H, Chandrahasan H. Effects of cigarette smoking on auditory function. Research in Otolaryngology. 2016;5(1):9-15.
16. Ahmed Sarah M. The effects of smoking and noise exposure on hearing sensitivity: A study on a Saudi population. King Saud University. 2018.
17. Hu H, Sasaki N, Ogasawara T, Nagahama S, Akter S, Kuwahara K, et al. Smoking, smoking cessation, and the risk of hearing loss: Japan epidemiology collaboration on occupational health study. Nicotine Tob Res. 2019;21(4):481-488.
18. Wang D, Zhu Y, Li C, Wang Y, Wang S, Wu S, et al. Relationship between cigarette smoking and hearing loss in China: A cross-sectional study in Zhejiang Province. Tob Induc Dis. 2021;19(4):40.