When taken separately, both syndromes have little incidence, which leads us to expect this incidence to be even lower when they are found on the same electrocardiogram. Incidentally, the current medical literature contains no publications on this topic. This clinical case aims to establish the existence of an electrocardiographic pattern characterised by WPW and a PQTS pattern on an ECG record. With a high susceptibility to crisis of tachycardia, especially at night, several episodes of syncope, even cardiac arrest.

The patient is a 24-year-old man. Since childhood, he has suffered from more than four tachycardia attacks, three documented syncope episodes, as well as two cardiac arrests recovered, for which he was treated with electric discharges. Afterwards, he was treated with radiofrequency ablation of Kent’s bundle, with permanent positive results so far (Figure 1).

Figure 1: Electro physiology Study. In the EPS graphic can be seen (arrow) typical signs of a WPW: Intracardiac electrogram showing under right ventricular pacing, atrial activation precocity in distal coronary sinus followed by His bundle.

Currently, our research team is working on features and management of this peculiar entity cardiology. Unfortunately, some are unknown to us yet.

The patient was positive for the gene of LQT1 (KCNQ1) (Figure 2).

Figure 2: Electro cardiogram recording (12 leads). The presence of WPWS and PQTS can be observed.

He had not taken any medication to induce QT interval prolongation.

The fundamental symptoms were strong palpitations (especially at night), crises of severe tachycardia (greater than 250 bpm), episodes of syncope documented, with total reduction of consciousness, hypovolemic shock, reaching suffering two cardiac arrests.

The patient specific medication was never against the long QT, since he was never diagnosed with it: The long QT went unnoticed by your physicians. Our research team was who discovered to the two entities together in the same record ECG.

Although is a WPW intermittent, in all leads there is always a prolonged QT interval (values greater than 0.480 seconds), as can be measured in the ECG recording.

Following ablation, the patient has not suffered similar symptoms so far. Possibly this is because the patient is with sodium blockers as treatment, currently:

Your physicians chose the drug “hydroquinidine hydrochloride” against the WPW (a sodium blocker channels, class I) by orally. Because it has a stabilizing effect on the myocyte membrane and the capsule form with allows a stable absorption hydroquinidine for 8-12 hours and avoids the “peaks “in the hematic concentration of the substance. The maximum dose is 12.9mg/kg/ day, orally in two intakes each 12 hours. The dose is interrupted or reduced when the arrhythmia is eliminated or improved, or if hypotension occurs, the QRS complex widens by 50% or more, or the maximum dose is achieved.

The risks of intoxication or adverse effects are also lower.

Since the patient remains without symptoms following the radiofrequency ablation, we decided to maintain the current treatment but with strict control of the patient.

QT interval duration following the ablation was similar to the duration before ablation. Ie, a prolonged QT.