Journal of Clinical Microbiology and Antimicrobials
Open Access

Antimalarial Medications

Antimalarial medication works by killing the malaria parasites during their development stage in the liver and red blood cells. ... Continuing to take antimalarial medication after leaving the risk area will prevent the parasites from establishing themselves. There are five species of human malaria parasitesAtovaquone/proguanil (Malarone), doxycycline, and mefloquine are the drugs of choice for malaria prevention in most malaria-endemic regions. Chloroquine (Aralen) may be used safely in all trimesters of pregnancy, and mefloquine may be used safely in the second and third trimesters of pregnancy.

It notes that malaria is also a seriously and potentially deadly infection. ... The United Nations estimates malaria kills more than 600,000 people every year, mostly children in Africa. But antimalarial drugs can cause serious side-effects. “Mefloquine may cause dizziness, balance problems, and ringing in the ears.All three are considered drugs of choice for travelers heading to most malaria-endemic regions. However, the study found, both atovaquone-proguanil — sold under the brand-name Malarone — and doxycycline appear to have fewer side effects.

It might be one of the following:

Atovaquone-proguanil (Malarone): You'll take this pill daily, starting 1 to 2 days before your trip, and you'll keep taking for a week afterward. ... Chloroquine: This drug is taken once a week, starting about 1 to 2 weeks before your trip and continuing for 4 weeks after.