ISSN: 2165-8056
Blastomycosis is an uncommon endemic fungal infection. It is presumed that in the endemic regions, the number of exposed individuals is significantly greater than those in whom clinical manifestations develop. We conducted a case-control study of individuals with clinical blastomycosis and controls with similar exposure but who did not develop disease. A genetic association was observed between the Gc-2 allele of vitamin D binding protein and reduced susceptibility to blastomycosis in a Canadian cohort. The Gc-2 allele can affect increased antimicrobial activity of macrophages. It may be possible to mimic this mechanism of protection by vitamin D supplementation.
Research Article: Fungal Genomics & Biology
Review Article: Fungal Genomics & Biology
Research Article: Fungal Genomics & Biology
Research Article: Fungal Genomics & Biology
Editorial: Fungal Genomics & Biology
Posters & Accepted Abstracts: Journal of Cell Science & Therapy
Scientific Tracks Abstracts: Journal of Cell Science & Therapy
Scientific Tracks Abstracts: Journal of Cell Science & Therapy
Posters: Journal of Cell Science & Therapy