Journal of Genetic Syndromes & Gene Therapy
Open Access

Fragile X Syndrome

Fragile X syndrome (FXS) is a genetic disorder characterized by mild-to-moderate intellectual disability. The average IQ in males is under 55, while about two thirds of females are intellectually disabled. Fragile X syndrome is a genetic condition that causes a range of developmental problems including learning disabilities and cognitive impairment. Usually, males are more severely affected by this disorder than females. Affected individuals usually have delayed development of speech and language by age 2.

Fragile X syndrome affects a child's learning, behavior, appearance, and health. Symptoms can be mild or more severe. Boys often have a more serious form of it than girls. People who have fragile X syndrome have learning and developmental disabilities, which can vary from mild to severe. It is a chronic condition that can significantly impair a person’s ability to live independently.