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The pathophysiology is very complex and has been only partially elucidated. Most people affected by the condition are older, obese, sedentary, and have a degree of insulin resistance. Stress can also be a contributing factor. The most important risk factors are diet (particularly sugar-sweetened beverage consumption),genetics aging, sedentary behavior or low physical activity, disrupted chronobiology sleep mood disorders/psychotropic medication use, and excessive alcohol use. There is debate regarding whether obesity or insulin resistance is the cause of the metabolic syndrome or if they are consequences of a more far-reaching metabolic derangement. Markers of systemic inflammation, including C-reactive protein, are often increased, as are fibrinogen interleukin 6 tumor necrosis factor-alpha (TNF-α), and others. Some have pointed to a variety of causes, including increased uric acid levels caused by dietary fructose
Review Article: Journal of Hematology & Thromboembolic Diseases
Editorial: Journal of Yoga & Physical Therapy
Research Article: Annals and Essences of Dentistry
Case Reports: Annals and Essences of Dentistry
Scientific Tracks Abstracts: Pediatrics & Therapeutics
Scientific Tracks Abstracts: Pediatrics & Therapeutics
Posters & Accepted Abstracts: Endocrinology & Metabolic Syndrome