Journal of Clinical Toxicology
Open Access

Toxicogenomics Impact Factor

Toxicogenomics investigates how the genome responds to environmental substances. Chemicals can change the expression of genes, proteins, and metabolites in living cells. Measuring genome-wide changes in affected tissues is useful for finding markers of toxicity or disease, and for understanding how genetic variation among individuals can influence sensitivity to a substance. Finding the doses at which a substance can cause changes in gene expression and other genome-related endpoints is also important in risk assessment.