ISSN: 2161-0932
Birtukan Derso Endalew
Bahir Dar University, Ethiopia
Posters & Accepted Abstracts: Gynecol Obstet (Sunnyvale)
Introduction: Intracranial tuberculoma in new born is a rare occurrence. We report a 7-month-old male infant presenting to our tertiary care referral center with complaints of global developmental delay and right hemiparesis for 3 months. Radiologic imaging was suggestive of large left frontoinsular space-occupying lesion with initial differential of primitive neuroectodermal tumor or desmoplastic infantile ganglioma. Considering the clinicoradiologic findings and no history suggestive of immunodeficiency or contact with tuberculosis, surgical decompression was done. Final histopathology revealed multiple epithelioid granulomas suggestive of tubercular etiology or intracranial Langerhans cell histiocytosis. He was started on antitubercular therapy after ruling out Langerhans cell histiocytosis using CD1a and Langerin immunohistochemistry staining. Interpretation of tuberculous etiology in infants can be challenging for clinicians, radiologists and pathologists. A high index of suspicion is necessary to diagnose such lesions, predominantly in endemic regions. Case Presentation: A 2500 gms neonate is born from a para-ii mother at a gestational age of 35 weeks. The mother had only two antenatal follow up. In the last two months before delivery she had productive cough, shortness of breath, easy fatigability. Obstetric ultrasound showed normal pregnancy. Labor started in a week. She delivered 2800 gms male with APGAR of 5 and 6 in the 1st and 5th minutes. With widened anterior fontanel, increased tones of lower extremity of the right side and progressively fails to suck. With investigation the problem is found to be tuberculoma.
Email: birtiederso@gmail.com