ISSN: 2376-0419
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Mitali Shrimanker and Riddhi Dave
Saraswati Institute of Pharmaceutical Sciences, India
Posters & Accepted Abstracts: J Pharma Care Health Sys
Diabetes mellitus is interminable metabolic issue that influence human body as far as physical, mental and social wellbeing. It is characterized as a gathering of clutters lipids, starches and proteins. It is turning into the third "executioner" of the soundness of humanity alongside malignancy, cardiovascular and cerebrovascular ailments. As we travel through life, the extent of each of the three doshas continually varies as indicated by your surroundings, our eating regimen, the seasons, the atmosphere, our age and numerous different elements. As they move into and out of parity, the doshas can influence your wellbeing, vitality level, and general temperament. Gymnema sylvestre is a woody, climbing plant of tropical backwoods of focal and southern India and in parts of Africa. Costus igneus normally known as blazing Costus, Step stepping stool or Spiral banner or Insulin plant, is local to South and Central America. Both the arrangement is utilized as a part of to diabetes. This research separate both the anti-diabetic plant by their pharmacognostic mean. Both the plants were studied for Morphological, Microscopically evaluation for leaf and stem part showed their inner cellular structure differed from each other. Physical evaluation includes ash value, extractive value, pH, Moisture content showed the quality of both the drug were up to the standard. Preliminary phytochemical examination through the chemical tests explains about the chemical nature of the plants and also explains the correlation between the chemical moiety and their pharmacological activity. TLC and HPTLC showed the quality and the quantity of the active compounds which are actively involved into the activity. Oxidation is also one of the causes for the diabetes. Antioxidant activity of both the plants was studied through the in-vitro models; DPPH model, Ferric reducing model and H2O2 which showed the good oxygen scavenging activity of both plants said Gymnema sylvestre and Costus igneus.
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