Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
+44 1478 350008
ISSN: 2155-9554
+44 1478 350008
Kaksha B Shah
Kaksha B Shah's Skin, Hair & Cosmetology Clinic, India
Posters & Accepted Abstracts: J Clin Exp Dermatol Res
Context: There are very few studies evaluating efficacy of platelet rich plasma (PRP) in hair restoration and its combination with microneedling. As far as ascertained, there is no study to evaluate efficacy of Microneedling with PRP + Topical minoxidil (5%) versus Topical minoxidil (5%) alone in androgenetic alopecia. Aims: 1) To compare the efficacy of a) Topical minoxidil (5%) alone and b) Topical minoxidil (5%) + Microneedling with PRP in men between 18 to 50 years with androgenetic alopecia grade 3 to 5 vertex (Norwood-Hamilton scale). 2) To perform objective and subjective evaluation based on clinical improvement and photographic evidence. Methods & Materials: Fifty patients with androgenetic alopecia were selected on the basis of inclusion and exclusion criteria. These patients were randomly divided into two groups of 25 patients each and were given following treatment. Group A: Topical minoxidil (5%) alone. Group B: Topical minoxidil (5%) + Microneedling with PRP (Platelet Rich Plasma) Statistical Analysis Used: Patients were assessed before starting the treatment and at the end of 6 months on the basis of: � Patient�s self-assessment based on standardized 7-point scale compared with baseline � Physician�s assessment based on standardized 7-point scale of hair growth compared with baseline Results: There was a significant improvement (p<0.05) in both patients� assessment and investigator�s assessment in group B as compared to group A at the end of 6 months. Conclusions: Thus Topical minoxidil (5%) + Microneedling with PRP turned out to be better treatment modalities than Topical minoxidil (5%) alone in this study. For drawing better conclusions, further studies are required to be done with larger sample size and longer duration of follow up to assess the effects of these treatments in androgenetic alopecia.
Email: kakshashah89@yahoo.co.in