ISSN: 2155-9570
Vishakha Dabhi
India
Posters & Accepted Abstracts: Clin Exp Ophthalmol
Introduction & Objective: Glaucoma is a major health problem. It is the third leading cause of blindness worldwide after
cataract. Primary open angle glaucoma is the most common form of glaucoma and is the leading cause of irreversible
blindness. Evaluation of Retinal Nerve Fiber Layer (RNFL) and Optic Nerve Head (ONH) is an essential step in the diagnosis
and monitoring of glaucoma. Early detection and treatment of glaucomatous optic neuropathy may reduce the incidence of
blindness from glaucoma. The aim of this study is to find correlation between RNFL loss and cupping of disc and visual field
changes in POAG patients.
Method: This is a non-randomized, open label, prospective study, undertaken in department of ophthalmology Sir T. Hospital
and Government Medical College, Bhavnagar after approval from Institutional Review Board. In our study 40 patients were
examined who have attended our OPD were diagnosed as having POAG basing on the Applanation tonometry, optic disc
changes and automated perimetry and RNFLT in OCT. Study data were entered and tabulated in Microsoft Excel 2007 and
analyzed by Statistical Package of Social Science (SPSS) used to compare mean values to find p values and ensuring statistical
significance.
Result: In our study we found correlation between vertical CDR and visual field changes statistically significant (BE-P<0.0001)
and also there is a correlation between vertical CDR and RNFL loss (RE-P<0.019, LE-P<0.007). In our study we also found
correlation between visual field changes and RNFL loss statistically significant. We also found that RNFL loss occur prior to
visual field changes. We have found that the visual field changes, vertical CDR and RNFL loss are correlating with each other
and consistent with the literature and other studies.
Conclusion: In our study we found correlation between RNFL loss and cupping of disc and visual field changes in POAG
patients. We also found that RNFL loss occur prior to visual field changes. Thus, it helps in early diagnosis and monitoring of
glaucomatous damage and helps to reduce the incidence of blindness from glaucoma.
E-mail: vishakhadabhi@gmail.com