Journal of Pharmaceutical Care & Health Systems
Open Access

Antibacterial activity and two-dimensional gas chromatography of Celtis africana extracts

4^th African Pharma Congress

June 20-21, 2016 Cape Town, South Africa

Nchabeleng Evonia Kanyane

University of Johannesburg, South Africa

Posters & Accepted Abstracts: J Pharma Care Health Sys

Abstract :

New infectious diseases and microorganisms resistant to our antibiotics emerge all the time. There is therefore constantly a need for new drugs that will eradicate these infections. Plants are considered as one of the main sources of biologically active compounds. Celtis Africana is a multipurpose tree used as an ornamental and medicinal plant; it is traditionally used for the treatment of cancer, pains, rheumatism and syphilis. In the current study aerial parts of the plant were dried and extracted with organic solvents of different polarities. The crude extracts were analysed using two-dimensional gas chromatography coupled with time-of-flight mass spectrophotometry (GCxGC TOF-MS) and they were further tested for antimicrobial activity. The plant showed activity against five significant pathogenic test organisms. The antimicrobial activity results correlate with the traditional medicinal uses of the plant. These results show potential for drug development using compounds produced by the plant.

Biography :

Email: evoniak@yahoo.com