Medicinal & Aromatic Plants
Open Access

Anti-fasciolic efficacy of some medicinal plants in comparison with triclabendazole in naturally infected buffaloes

5^th International Conference & Exhibition on Herbal & Traditional Medicine

November 05-06, 2018 | London, UK

Asma Waheed Qureshi, Akhtar Tanveer and Azhar Maqbool

GC Women University, Pakistan
University of the Punjab, Pakistan
University of Lahore, Pakistan

Scientific Tracks Abstracts: Med Aromat Plants

Abstract :

The current study Caesalpinia crista (seeds) and Saussurea lappa (roots) were used to treat buffaloes naturally infected with fasciolosis and their efficacy (%) was compared with triclabendazole. A total of 81 (72 infected and 9 normal healthy) buffaloes (Bubalus sp.) of Nili Ravi breed, 6.0±0.1 years of ages and both sexes naturally infested with fasciolosis were used for anthelmintic trails. The infected buffaloes were randomly divided into four main groupsâ?? i.e. C, S, T and I. Animals in groups C and S were further sub divided into three sub groups i.e. C1, C2, C3; S1, S2, S3, each having nine animals. Two more infected groups T and I also have nine infected animals each while group G with nine healthy normal animals. Sub-groups C1 and D1 were given dose level of 50 mg/kg body weight, C2 and D2, 100 mg while C3 and D3, 150 mg/kg body weight of crude Caesalpinia crista (seeds) and Saussurea lappa (roots), respectively. Group T was given triclabendazole (10 mg/kg body weight). While for the comparison of animals in I and G served as infected and healthy control groups, respectively. Efficacy (%) for triclabendazole was 100% after first dose while for the two herbal medicine, after administration of second dose of 150 mg/kg body weight. Anti-fasciolic effects of these plants may be due to the presence of metabolites like alkaloids, tannins, saponins, phenolic compounds and flavonoids. The two plants were found significantly (P<0.05) effective and safe to use against fasciolosis.

Biography :

Asma Waheed Qureshi has completed her PhD at University of The Punjab, Pakistan in 2010. Currently, she is working as an Associate Professor and Head of The Department of Zoology at GC Women University, Sialkot, Pakistan. She has published more than 20 research articles in reputed journals and presented papers in national and international conferences.

E-mail: asmawqureshi@yahoo.com