Journal of Glycomics & Lipidomics
Open Access
ISSN: 2153-0637
ISSN: 2153-0637
Anthony Okhonlaye Ojokoh
Federal University of Technology, Nigeria
Posters-Accepted Abstracts: J Glycomics Lipidomics
The antimicrobial activities and phytochemical properties of Alstonia boonei, Jatropha multifida and Rauvolfia vomitoria were studied using the impregnated disc diffusion technique. Seven clinical bacterial species viz: Staphylococcus aureus, Escherichia coli, Bacillus cereus, Pseudomonas aeruginosa, Streptococcus faecalis, Proteus vulgaris and Streptococcus pyogenes, and three fungal species viz: Candida albicans Aspergillus niger and Aspergillus flavus were used. The chloroform and hot water extracts of Alstonia boonei exerted zones of inhibition ranging from 6-10mm. Chloroform, ethanolic and hot water extracts of Rauvolfia vomitoria exerted zones of inhibition ranging from 5-10 mm. Also that of the ethanolic, cold and hot water extracts of Jatropha multifida ranged from 5-15 mm. Hot water extract of Alstonia boonei was active against Staphylococcus aureus, Escherichia coli, Streptococcus faecalis. Ethanolic extract of Rauvolfia vomitoria was active against Pseudomonas aeruginosa and Staphylococcus aureus. Also Bacillus cereus and Proteus vulgaris were susceptible to the ethanolic extract of Jatropha multifida. None of the extracts has antimicrobial activity against the fungal species likewise ethanolic and cold water extracts of Alstonia boonei; cold water extract of Rauvolfia vomitoria and chloroform extract of Jatropha multifida and which have no effect on none of the test isolates. The MIC values of the extracts ranged between 40 and 80 mg/ml. The three plants screened had similar phytochemicals except in few cases like saponnins, tannins, Keller-killiani and Liberman�s test. None contains phlobatannins and anthraquinone. The statistical analysis at 95% level of significance showed that Jatropha multifida is most effective. All the three plants had broad spectrum antibacterial activities against one or more gram-positive and gram-negative bacteria. The antimicrobial activities and phytochemical properties of these extracts provide justification for the chemotherapeutic utilization of the plants and could serve as useful sources for new antimicrobial agents.
Email: tonyojokoh@yahoo.com