Journal of Clinical and Cellular Immunology
Open Access
ISSN: 2155-9899
ISSN: 2155-9899
Florentina Silvia Delli
Department of Dermatology, Aristotle University of Thessaloniki
Scientific Tracks Abstracts: J Clin Cell Immunol
Pemphigus Vegetans (Hallopeau, Neumann) Endemic Pemphigus, Pemphigus Erythematous, Pemphigus Herpetiformis, Drug-induced Pemphigus. Group of life-threating autoimmune bullous diseases characterized by flaccid blisters and erosions of the mucous membranes and/or skin. Progressive course – severity of the disease. Before corticosteroids almost always fatal within 2 years after diagnosis. Pathophysiologically – Autoantibodies against the desmosomal adhesion protein. Rare – Central Europe 2 new patients per 1 million in habitants per year in Central Europe. PV 3 subtypes are Mucosal dominant PV (Antibodies restricted to Dsg3 Blisters in deep layers of the oral mucosa), Mucocutaneous PV (Antibodies against Dsg1and Dsg3 Involvement of the dermis in addition to the mucous membranes), Cutaneous PV type (Less frequent blistering in deep epidermal layers owing to anti-Dsg1 and pathogenically weak anti-Dsg3).
Florentina Silvia Delli is from Aristotle University of Thessaloniki, Greece and specialized in Dermatology. Published articles related to skin diseases and dermatology. Research interests are skin disorders, skin Comorbidities, auto immune diseases and many more.