Journal of Clinical and Cellular Immunology
Open Access
ISSN: 2155-9899
ISSN: 2155-9899
Banchamlak Zereay, Yared Assefa, Feleke Moges, Mengistu Endris, Bemnet Amare, Damtew Bekele, Solomon Tesfaye, Mulu and Yeshambel Belyhun
University of Gondar, Ethiopia
Posters-Accepted Abstracts: J Clin Cell Immunol
Background: Bacterial pathogens isolated from dacryocystitis patients are diverse and complex in terms of their distribution, prevalence, and antimicrobial susceptibility pattern. The clinical importance of microbial causes of dacryocystitis and pattern of drug resistance has not been reported in northwest Ethiopia. Moreover, the management of dacryocystitis is based on only clinical observation. Therefore, this study attempted to identify and define clinical and microbiological characteristics of microbial agents of dacryocystitis and its antibiotic susceptibility patterns. Methods: A cross sectional study was conducted from January 2011-January 2012 among dacryocystitis patients attending ophthalmology outpatient department of Gondar University Teaching Hospital. Socio demographic and clinical data collection, microbiological analysis and antibiotic susceptibility test patterns were done following standard procedures. Results: From the total of 51 dacryocystitis cases, bacterial origins were isolated among 31(60.8%) cases. The dominant isolates were Coagulase Negative Staphylococci (CNS) 9(29.0%), Staphylococcus aureus 6(19.4%) and Pseudomonas species 3(9.7%). S. pneumoniae, Enterobacter species, K. pnemoniae and H. influenzae were each accounted 6.5% isolation rate. Among the commonly prescribed antimicrobials tested for susceptibility pattern; amoxicillin 38.7%, ciprofloxacin 25.8%, chloramphinicol 25.8%, co-trimoxazole 25.8%, and ampicillin 19.4% were resistant to the overall bacterial isolates identified. Only Citrobacter species were sensitive to all antibiotics tested but the rest bacterial isolates were resistant for at least to one, two, three, four and more antibiotics tested. Overall, 9(29.0%) of the bacterial isolates were resistant to only one antibiotic and resistance to two, three and four antibiotics each accounted 5(16.1%) rate. Conclusions: Though the information derived from this study was very meaningful, further studies encompassing viral, fungal, parasitic and anaerobic bacteria origin are important to better define the spectrum and relative incidence of pathogens causing dacryocystitis. Microbiological analysis and anti-microbial susceptibility pattern is mandatory for the selection of a specific anti-microbial therapy and to the control of further resistance development of bacterial strains.
Email: bzeraye@yahoo.com