Organic Chemistry: Current Research
Open Access

Biomimetic total synthesis - Examples from different classes of heterocyclic natural products

International Conference on Organic Chemistry

August 10-11, 2016 Las Vegas, Nevada, USA

Christian B W Stark

University of Hamburg, Germany

Posters & Accepted Abstracts: Organic Chem Curr Res

Abstract :

Biomimetic natural product total synthesis can be a valuable strategy for the assembly of complex target molecules. It remains a powerful concept even 100 years after its first mention (and application) in literature. Mimicry is often particularly effective when it comes to establishing sterically encumbered substructures or polycyclic frameworks. In addition, speculation on biosynthetic pathways can sometimes be used to postulate the most likely constitution or configuration and sometimes even allow to predict the structure of an as yet undiscovered metabolite. A putative biomimetic synthesis can then be used to confirm (or correct) the structure of the respective natural product.

Biography :

Email: stark@chemie.uni-hamburg.de