Journal of Nutrition & Food Sciences
Open Access

Chemical composition of essential oil and in vitro antibacterial and anticancer activity of the hydroalcolic extract from Coronilla varia

2^nd International Conference on Nutraceuticals and Nutrition Supplements

July 18-19, 2016 Bangkok, Thailand

Dehpour Abbas Ali

Islamic Azad University, Iran

Posters & Accepted Abstracts: J Nutr Food Sci

Abstract :

The essential oils of Coronilla varia is obtained by hydrodistillation and analyzed by (GC/MS) for determining their chemical composition and identification of their components .The major components were Caryophyllene Oxide (60.19%), Alphacadinol (4.13%) and Homoadantaneca Robexylic Acid (3.31%). The extracts from Coronilla varia had interesting activity against Proteus mirabilis in the concentration 700 �¼g/disc and did not show any activity against Staphylococus aureus, Bacillus subtillis, Klebsiella pneumonia and Entrobacter cloacae. The positive control, Ampicillin, Chloramphenicol and Cenphalothin had shown zone of inhibition resistant all bacteria. The effect of hydroalcoholic extracts from Cornilla varia investigated on Hela cancer cell line. Corohilla varia ethanol extract could inhibit the proliferation of Hela cell line in RPMI 1640 medium. LC50 5 (mg/ml) was the optimum concentration of extract from Coronilla varia inhibition of cell line growth. The Hela cancer cell line was more sensitive to Coronilla varia ethanol extract.

Biography :

Email: dehpour@gmail.com