Biochemistry & Pharmacology: Open Access
Open Access

Chromatographic separation of some antiepileptic drugs

9^th World Congress on Pharmacology

September 04-06, 2017 | Paris, France

A Hamdi

USTHB, Algeria

Posters & Accepted Abstracts: Biochem Pharmacol (Los Angel)

Abstract :

In the present studies, chromatographic separation of some antiepileptic drugs,diazepam,valproic acid and verapamil after intravenous and oral administration to rats have been conducted .Stationary phase and mobile phase have been chosen and the parameters of mobile phase have been determined.Also pharmacokinetic parameters have been investigated.Reversed phase column (125x4.6 mm.i.d.)nucleosil 100-5 C18 with mobile phase consisting of ACN/butter phosphate,75mmol,ph3(40/60 v/v%)and wave length 230nm.