ISSN: 2155-9880
+44 1300 500008
Sekib Sokolovic
University Clinical Center Sarajevo, Bosnia and Herzegovina
Keynote: J Clin Exp Cardiolog
Introduction: The correlation between the arterial stiffness and tobacco users has been verified in a clinical study. Increased
arterial stiffness contributes to increased vascular calcifications and atherosclerotic disease and all cardiovascular mortality.
Cigarette smokers contribute to 6 million deaths per year globally. Measurement of the arterial stiffness has been recommended
in the ESC/ESH guidelines for the arterial hypertension.
Material & Method: In order to evaluate the arterial stiffness, the measurement of aortic pulse wave velocity, (APWV),
augmentation index (AI), stroke volume, (SV), the reflection gradient (RC) was performed using Agedio Arteriograph. The
estimation of cardiovascular risk factors was performed in all examined patients and two groups were formed. One group included
smokers and the other one non-smoker healthy subjects. The open outpatient controlled prospective study has been designed. The
cardiovascular others risk factors were evaluated in all.
Results: Preliminary results obtained have shown the significant increase in APWV, augmentation index and reflection index in
smokers group compared to normal arterial stiffness values in non-smokers.
Conclusion: These preliminary results have shown that arterial stiffness has been significantly increased in a smoker group
whereas the average vascular age has been increased. This finding is additional evidence for the cigarette smoking as risk factor
for early vascular pathophysiological changes. The measurements of these parameters are necessary for the cardiovascular risk
disease prevention.
,b.Recent Publications
1. Hanan Qasim, Zubair A Karim, Jose O Rivera, Fadi T Khasawneh and Fatima Z Alshbool (2017) Impact of electronic
cigarettes on the cardiovascular system. Journal of the American Heart Association 6:e006353J.
2. SzoÃ?Â?tysek - BoÃ?Â?dys I, Sobczak A, ZieliÃ?Â?ska-Danch W, BartoÃ?Â? A, Koszowski B and KoÃ?Â?mider L (2014) Influence of
inhaled nicotine source on arterial stiffness. Przeglad Lekarski 71(11):572-5.
3. Robert J Doonan, Anais Hausvater, Ciaran Scallan, Dimitri P Mikhailidis, Louise Pilote and Stella S Daskalopoulou
(2010) The effect of smoking on arterial stiffness. Hypertension Research 33(5):398�410.
4. Gupta R, Gurm H and Bartholomew J R (2004) Smokeless tobacco and cardiovascular risk. JAMA Internal Medicine
164(17):1845-9.
5. Asplund K (2003) Smokeless tobacco and cardiovascular disease. Progress in Cardiovascular Diseases 45(5):383-94.