Anesthesia & Clinical Research
Open Access

Comparative evaluation of Clopidogrel and Aspirin on early outcome of patients undergoing off pump CABG

Joint Event on 2^nd World Congress on Surgeons & 12^th International Conference on Anesthesiology and Critical Care

November 11-12, 2019 | Istanbul, Turkey

Hamid Reza Soltani and Seyed Khalil Forouzannia

Shahid Sadoughi University of Medical Sciences, Iran

Posters & Accepted Abstracts: J Anesth Clin Res

Abstract :

Introduction: Coronary artery by-pass graft surgery is the most common cardiac surgery performing widely round the world and recent evidence has demonstrated that post-operative tendency to formation of clod is very high. This study is designed to evaluate the effect of Aspirin and Clopidogrel on early outcome of patient undergoing OPCABGS.

Material & Methods: During this clinical trial study that was done on 281 patients (n=155 Clopidogrel regime, n=126 Aspirin regime) undergoing OPCABGS from Jan 2010 to July 2011. Mean age was 61.81±10.84 years. Background variables were analyzed by early outcome of patients using chi-square in SPSS software.

Finding: According to our data there was no significant relation between post operation DVT and post operation CVA, bleeding, mortality rate with antiplatelet regime (p>0.05).

Conclusion: Although Clopidogrel is a more expensive and newer drug but it seems that its effects on post of operation outcome does not differ from Aspirin so that according to this study Clopidogrel cannot be considered as qualified replacement instead of Aspirin rather combination antiplatelet therapy is also controversial.

Biography :

Hamidreza Soltani has his expertise in designing and managing the clinical researches and healthcare projects focusing on surgical studies. Over the years of doing clinical studies, He has won several national awards from various conferences. Since 2010, he has begun new activities on modern research-based treatment methods using telemedicine knowledge. He is currently working on designing a multinational virtual therapy network that will be able to provide the best medical consults to patients anywhere in the world in the shortest possible time with the major goal of reducing treatment costs and utilizing the expertise of the best professionals, especially cancerous patients.