Journal of Developing Drugs

Journal of Developing Drugs
Open Access

ISSN: 2329-6631

+44 1478 350008

Comparative study between general and thoracic Q1 spinal anesthesia for laparoscopic cholecystectomy


Joint International Conference and Expo on Industrial Pharmacy & 5th Global Pharmacovigilance Summit

April 28-29, 2016 Dubai, UAE

Mohamed Ellakany

Alexandria University, Egypt

Posters & Accepted Abstracts: J Develop Drugs

Abstract :

Background: Laparoscopic cholecystectomy is usually done under general anesthesia, but many patients with major medical problems sometimes cannot tolerate such anesthesia, and thoracic spinal anesthesia may be beneficial in such patients. A comparative study between two groups of patients submitted to laparoscopic cholecystectomy using either general anesthesia or segmental thoracic spinal anesthesia. Aim: The aim of this study is to compare discharge time, patient, and surgeon satisfaction between two groups of healthy patients submitted to laparoscopic cholecystectomy under general and segmental thoracic spinal anesthesia. Patients & Methods: Forty patients classified according to American Society of Anesthesiology (ASA) as class I or II undergoing laparoscopic cholecystectomy, divided into two groups, 20 patients each. Group G received conventional general anesthesia with endotracheal intubation and mechanical ventilation, and group S received a segmental (T10-11 injection) thoracic spinal anesthesia (through combined spinal epidural) using 1 ml of plain bupivacaine 0.5% (5 mg) in addition to 25 lg fentanyl. In group S, drugs to manage patient anxiety or hemodynamic perturbations (bradycardia or hypotension) were given when needed. Intraoperative monitoring, postoperative pain, complications, recovery time, and patient satisfaction at follow-up were compared between the two groups. Results: As regards the thoracic spinal group, spinal anesthetic was performed easily in all 20 patients, although two complained of paresthesia, which responded to slight needle withdrawal; the block was effective for surgery in all 20 patients, and five experienced some discomfort, which was readily treated with small doses of fentanyl, but none required conversion to general anesthesia; five patients required midazolam for anxiety, eight patients required ephedrine and atropine for hypotension and bradycardia, and recovery was uneventful and without sequelae. Conclusion: Patients received segmental thoracic spinal anesthesia had shorter discharge time and better satisfaction. Surgeon satisfaction was higher in general anesthesia group. Segmental thoracic spinal anesthesia can be used successfully and effectively for laparoscopic cholecystectomy in healthy patients by experienced anesthetists.

Biography :

Email: mlakany@yahoo.com

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