Pediatrics & Therapeutics
Open Access
ISSN: 2161-0665
+44 1478 350008
ISSN: 2161-0665
+44 1478 350008
Paloma Manea
University of Medicine and Pharmacy â??Gr.T. Popaâ?, Romania
Scientific Tracks Abstracts: Pediat Therapeut
MASS phenotype associates skeletal features, one of them being temporo-mandibular disorder (TDM). Apparently an innocent condition, TDM affects life quality, provoking symptoms like headache, neck and shoulder pain, dizzeness, tinitus and even deafness. Connective tissue in fibrilinopathies has the same abnormalities in the mitral valve, as well as in temporo-mandibular joint and this affirmation has been proved by multiple studies during last decade. We selected 46 children, diagnosed with MASS phenotype, aged between 5-17 years, with a predominance of females (70%). They were monitorized for 24 months, quarterly, using cardiological and dental examination, Ghent revised criteria, electrocardiogram, echocardiogram and magnetic resonance imaging (MRI) for temporo-mandibular joint. 40% of the patients (18 of 46) associated TMD, proved by dental examination and MRI. 6 of these 18 patients with TMD revealed a severe dysfunction of this joint and all of them increased their dyspneea (as symptom) and their mitral regurgitation, pulmonary pressure values, during 24 months observation. As an invasive investigation of mitral degeneration (biopsy) is not the best option for deciding the surgical moment, we consider that non-invasive assesment of temporomandibular joint, in this fibrillinopathy, could be a useful prognosis marker for mitral deterioration (if abnormalities of connective tissue are similar). We have made an adequate and in time selection of those 6 patients with cardiac surgical indication, so we reffered them to the cardiac surgeon and weâ??ve made this decision acounting the following: Worsening dyspneea, suported by augmented mitral regurgitation, pulmonary pressure values and a non-conventional, but very precise marker of connective tissue deterioration: MRI of temporo-mandibular joint affected by dysfunction.
Paloma Manea, MD, PhD, FACCP is a Specialist in Cardiology and Internal Medicine, competence in echocardiography, Lecturer at ’’Grigore T. Popa’’ University of Medicine and Pharmacy, Iasi, Romania. She was admited to ‘’Emil Racovita” high school in 1980, at first position, with 10 mark (written test at Mathematics and Roumanian Language). She was admitted to “Grigore T. Popa” University of Medicine and Pharmacy, Faculty of Medicine , in 1984, at first position (from 4,500 candidates), with 9.96 mark (written tests at Biology, Chemistry and Physics).
Email: maneacpaloma@yahoo.com