Biochemistry & Pharmacology: Open Access
Open Access
ISSN: 2167-0501
+44-77-2385-9429
ISSN: 2167-0501
+44-77-2385-9429
Biren N. Shah
Accepted Abstracts: Biochem & Pharmacol
Background: The present investigation was aimed to formulate transdermal films incorporating herbal drug components. The allopathic system of medicine includes two conventional lines of treatment for inflammatory diseases, which come along with certain side effects. Hence, turning to safe, effective and time-tested Ayurvedic herbal drug formulation would be a preferable option. Materials and Methods: With this view, transdermal films incorporating herbal drug components such as aqueous extract of fruits of Abelmoschus esculentus, Lagenaria siceraria and Trichosanthes dioica were envisaged. The polymeric films were evaluated for their physical properties like thickness, weight uniformity, moisture content, folding endurance, tensile strength and diffusion studies. The skin irritation study done on rat skin showed that the formulation does not produce irritation to the skin. Results: The formulation is screened for its anti-inflammatory potential and it is found to significantly reduce the paw edema by 60% when compared with the standard drug diclofenac i.e. 70%. Conclusion: Overall, it was observed that the well-known ayurvedic drugs have been found to be effective through modern pharmaceutical formulation techniques.