Journal of Physical Chemistry & Biophysics
Open Access
ISSN: 2161-0398
+44 1478 350008
ISSN: 2161-0398
+44 1478 350008
Anna A Khachaturova
National Academy of Sciences of Armenia, Republic of Armenia
Posters-Accepted Abstracts: J Phys Chem Biophys
The idea of our technology (product) is optical screening and imaging of highly scattering and/or absorbing thick media, including biological objects such as human palm and wrist, with spatial resolution and contrast adequate for imaging the bone and vascular structure, showing simple fractures, etc. We offer a device for straightforward optical transmission imaging of biological tissues. The key problems of optical transmission imaging of thick complex biological objects are strong diffusion (scattering) and non-uniform intensity distribution of transmitted signal across the scanned area. These constraints essentially reduce the spatial resolution and uniformity of the overall pattern. We report on implementation of a new approach of signal detection scheme, which relies on synchronization of lock-in amplifier with a temporal step of laser beam discrete scanning. This technique is favorable for preferential detection of abrupt spatial features, increase of contrast and substantial reduction of overall non-uniformity of image brightness. On the other hand, the lock-in detection scheme, being phase-sensitive, helps to some extent to enhance the contribution of least-deflected photons in the recorded signal thus suppressing the diffusion component. We present the results of measurements showing efficiency of the proposed scheme.
Email: annakhachat@mail.ru