Pediatrics & Therapeutics
Open Access
ISSN: 2161-0665
+44 1478 350008
ISSN: 2161-0665
+44 1478 350008
Katarzyna Mazur-Melewska, Aleksandra Derwich, Szymon Melewski, Wojciech Sluzewski and Magdalena Figlerowicz
Karol Marcinkowski University of Medical Sciences, Poland
Poznan University of Medical Sciences, Poland
Posters & Accepted Abstracts: Pediatr Ther
Introduction: Acute acalculous cholecystitis (AAC) is a rare complication of infectious mononucleosis with only a few cases reported among pediatric population. Purpose: Th e aim of this study was to evaluate clinical factors such as age, gender, predisposing diseases, laboratory results and ultrasonographic fi ndings that determine clinical outcome of AAC during IM in children. Methods: Retrospectively we analyzed the documentation of 168 children with IM hospitalized in Department of Infectious Diseases and Child Neurology in Poznan in 2012-2016. Clinical symptoms, physical examination fi ndings and diagnostic test results such as serologic tests, blood morphology, activity of aminotransferases and abdominal ultrasonography were thoroughly reviewed for all study participants. IM was confi rmed on the presence of the viral capsid antigen IgM antibodies. All patients were treated with intravenous acyclovir. Results: In the analyzed group we found 13 children (7.75%) with ACC diagnosed at the admission time. Th e mean age of children presented IM without cholecystitis was 7.66�?±5.44 years and children with ACC: 8.69�?±4.69 years (p=0.35). Th e gender distribution was similar in both groups (Boys: 60.65% and 61.54%; Girls: 39.35% and 38.46%, respectively). Th e diff erences in the number of leucocytes and monocytes, activity of aminotransferases in both analyzed groups were not statistically signifi cant. Th e ultrasonographic criteria for the diagnosis of AAC, signifi cant distention of gall bladder wall was found in 10 of 13 patients; GB wall thickness in 7; GB sludge and pericholecystic fl uid were identifi ed in 3 and 1 patients, respectively. Conclusion: Th e risk for AAC in children with EBV infection was estimated 7.75%. AAC can be seen in all-ages children with IM. Classical lab tests are not helpful in AAC diagnosis in children with EBV infection. AAC should be diagnosed basing on the abdominal ultrasonography, which should be the routine procedure in children with IM.
Katarzyna Mazur-Melewska is an Assistant Professor in Department of Infectious Diseases and Child Neurology at Karol Marcinkowski University of Medical Sciences in Poznañ, Poland. She has completed two specializations: Pediatrics and Infection Diseases. She is the author and co-author of 75 articles presented in national and international journals.