Journal of Glycomics & Lipidomics
Open Access
ISSN: 2153-0637
ISSN: 2153-0637
Egbung G.E, Etim G.O, Ubaba M.U and Atangwho I.J
University of Calabar, Nigeria
Posters-Accepted Abstracts: J Glycomics Lipidomics
Effects of dried Vernonia calvoana leaf (VCL) supplemented diets on selected lipid parameters and body weight changes were investigated in this study. Twenty four male Wistar rats (100-170g) were distributed into 4 groups of 6 rats each. Group 1 served as the control and received normal rat chow. Groups 2, 3 and 3 received the rat chow but with 5%, 15% and 30% incorporation of VCL, respectively for 31 days. Animals� body weights were measured once in every two days throughout the experiment period. At the end of the 31-day feeding the animals were fasted 12 hours prior to sacrifice. Blood was obtained via cardiac puncture and subjected to centrifugation in order to obtain sera for biochemical assay. Results show non- significant (P>0.05) increase in serum Alkaline phosphatase concentrations relative to the control. There was a marked increase in serum total protein levels though not significant. Body weight changes were significantly reduced in groups 3 and 4(15% and 30% supplementation) relative to the control. We therefore conclude that dietary supplementation of Vernonia calvoana leaf possesses probable body weight reducing potentials and also a protein biosynthesis promoting action.