ISSN: 2161-0398
+44 1478 350008
Shelley D Minteer
University of Utah, USA
Posters & Accepted Abstracts: J Phys Chem Biophys
Oxidoreductase enzymes have been employed for almost 5 decades in biosensors and for energy conversion in the form of biofuel cells. However, most enzymatic bioelectrodes in the literature utilize complex biofuels (e.g. glucose), but only partially oxidize the complex biofuel via the use of a single enzyme (i.e., glucose oxidase or glucose dehydrogenase). This presentation will detail the use of enzyme cascades at bio-anodes for deep to complete oxidation of substrates to improve performance (energy density, current density and power density), but will also focus on the importance of forming metabolons for substrate channeling in multi-enzyme cascades. This enzyme cascade will include natural metabolons (i.e. the Krebs cycle) and artificial metabolons utilizing DNA as a scaffold, as well as hybrid cascades with organic electrocatalysts. In this presentation, the author will discuss the importance of structural orientation of enzymes and enzyme complexation in enzymatic cascades for efficient bioelectrocatalysis.
Email: shelleyminteer@gmail.com