Clinical & Experimental Cardiology
Open Access
ISSN: 2155-9880
+44 1300 500008
ISSN: 2155-9880
+44 1300 500008
Rahul Mandole, Jagdish Hiremath and Atul Marvah
Madhavbaug Cardiac Care Clinics and Hospitals, India
Madhavbaug Institute of Preventive Cardiology, India
Sushrut Hospital and Research Center, India
Scientific Tracks Abstracts: J Clin Exp Cardiology
Ischemic heart disease (IHD) incidence has increased in India at a rapid speed and shows regional variations, early onset, greater mortality and poor management. Stress thallium test is useful in diagnosing IHD early in patients who may be at risk for a heart attack. The aim of the present study was to assess the cardiac muscle activity in IHD patients before and after ischemic reversal programme (IRP). The present open label study involved 14 IHD patients who underwent IRP (21 IRP sittings) in Madhavbaug clinics (multicentric). The inclusion criteria were subjects with known IHD, age group between 40-70 yrs, BMI > 20 kg/m2, and stress test positive for inducible ischemia. However, subjects with recent myocardial infarction/ known hypo- or hyper- thyroidism/ chronic kidney disorder were excluded. Stress thallium test was performed after enrolment, 21 IRP sittings and 25-30 IRP sittings. VO2max and time of ischemia after stress test were also recorded in all the patients. Further, Seattle Angina Questionnaire (SAQ) was taken via telephonic conversation by research coordinators. Observations from stress thallium test showed significant difference in Summed Stress Score [SSS] (13.5�±10.3, baseline vs. 10.7�±10.1, post 21 IRP sittings; p=0.01) as well as Summed Difference Score [SDS] (8.9�±6.2, baseline vs. 6.2�±6.3, post 21 IRP sittings; p=0.03) in IHD patients. Similarly, we observed increase in VO2max levels (12.8�±5.7, baseline; 19.4�±7.8, post 21 IRP sittings and 23.6�±6.0, post 25-30 IRP sittings) and time of ischemia in seconds (370.7�±201.1, baseline vs. 597.8�±201.9, post 21 IRP sittings and 702.0�±138.0, 30-days follow-up). Further assessment of SAQ scores showed significant improvement post IRP (30.2�±3.6, baseline vs. 32.7�±3.5, post 21 IRP sittings) whereas, ejection fraction score was not found to be significantly changed post IRP as compared with baseline. Results of the present study suggest an improvement in cardiac muscle activity after IRP in IHD patients and depicts positive role of IRP in IHD management.
Rahul Mandole is the first to conceptualize the idea that ancient Indian Medical Science, Ayurveda, can play a big role in chronic cardiac disease. He is the founder of Madhavbaug Clinics & Hospitals in India, used his education in Modern Medicine and undertook a meticulous research into Ayurveda. Extensive experimentation and delving deeper into every minute aspect of his study led him to find scientific evidence to substantiate this novel idea. His effort resulted in a combination of modern medical science and the well-established therapies prescribed in Ayurveda, which could prove highly effective alternative way to treat chronic heart failure.
Email:drrahulmandole@gmail.com