Journal of Clinical & Experimental Dermatology Research

Journal of Clinical & Experimental Dermatology Research
Open Access

ISSN: 2155-9554

+44 1478 350008

Instant barrier repair: Investigating occlusion with a new hydro gel patch for the treatment of atopic dermatitis


International Conference & Exhibition on Clinical Research Dermatology, Ophthalmology & Cardiology

5-6 July 2011 San Francisco, USA

Kelly K Park

Scientific Tracks Abstracts: JCEDR

Abstract :

The ideal repair mechanism for overcoming barrier disruption in atopic dermatitis (AD) needs to completely eliminate microbe and allergen penetration as well as transepidermal water loss. The hydro gel patch may be an innovative approach to complete barrier repair through its innovative properties as a new, innovative occlusive dressing that consists of a water-rich hydro gel layer on an impermeable urethane backing. A 6-week pilot study with 15 AD patients, who applied the hydro gel patch over one lesion for 6-8 hours daily and triamcinolone (TAC) 0.1% cream twice daily to another lesion. Results after 2-week no treatment follow-up showed hydro gel patch had notable efficacy, and comparable to TAC 0.1% cream. Larger studies are needed to validate these promising results. In addition, although the hydro gel patch was originally designed to be used in combination with topical medications for treatment of both psoriasis and eczema, preliminary data shows that the patch is effective for eczema by itself. It is hypothesized that this may be due to ?instant? repair of the defective skin barrier seen in patients with atopic dermatitis. This provides a safe, effective, non-steroidal option for patients with eczema.

Biography :

Dr. Park is the Clinical Research and Phototherapy Fellow at the University of California at San Francisco (UCSF) Psoriasis Tre atment Center and Phototherapy Unit of the Department of Dermatology and is experienced in both industry sponsored and investigator initiated cli nical trials. Dr. Park graduated from both the University of Akron with a double major in Natural Sciences and History and the North eastern Ohio Univ ersities College of Medicine (NEOUCOM) as in the 6-year accelerated BS/MD program. At NEOUCOM, she earned her Bioethics Certi fi cate as part of the inaugural class of the Bioethics Certi fi cate Program. She then completed her internship in Internal Medicine at the historic St. Vincent?s Hospital Manhattan in New York as part of the hospital?s fi nal graduating class. Dr. Park is a proli fi c author and has published in the British Medical Journal, Cutis, Journal of Drugs and Dermatology, and Up To Date

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